A Study Of Correlation Between Serum Lipid Profile And Iron Deficiency Anemia In Indian Patients
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Date
2025-07
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Publisher
The Indian Society for Health and Advanced Research
Abstract
Background: Iron deficiency anemia (IDA) is a prevalent condition globally, particularly in India, where it affects a significant proportion of the population. Dyslipidemia, characterized by abnormal lipid levels, is also common and linked to cardiovascular risks. The relationship between IDA and lipid profile alterations remains underexplored. This study aimed toObjective: evaluate the association between IDA and serum lipid profiles, assess demographic and clinical features of anemic patients, and determine if anemia severity or type influences lipid sub-fractions. A prospective case-control study was conducted at Chigateri General HospitalMethods: and Bapuji Hospital, Davangere, India, from April 2021 to August 2022. Fifty patients with IDA (hemoglobin <13 g/dL for men, <12 g/dL for women) and 50 age- and sex-matched non-anemic controls were included. Fasting lipid profiles (total cholesterol, triglycerides, HDL, LDL, VLDL), iron profiles (serum ferritin, iron, TSAT, TIBC), and complete hemograms were analyzed. Statistical analysis used the Mann-Whitney U test, Chi-square test, and Spearman's correlation, with p<0.05 considered significant. IDA patients had significantly lower hemoglobinResults: (7.84±2 g/dL vs. 12.8±0.8 g/dL, p<0.05), RBC count (2.87±0.83 vs. 4.36±0.3 million cells/mcL, p<0.05), and PCV (19.6±7.2% vs. 37.08±3.7%, p<0.05) than controls. Total cholesterol (136.06±20.9 vs. 145.5±28.3 mg/dL, p=0.04) and LDL (81.8±14.2 vs. 88.8±19.4 mg/dL, p=0.03) were significantly lower in IDA patients. Positive correlations were found between anemia and lipid sub-fractions (p<0.05), but no significant correlation existed with serum ferritin. IDA is associated with hypocholesterolemia, particularly in total cholesterol and LDLConclusion: levels. Regular lipid profile monitoring in IDA patients is recommended.
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Keywords
Iron Deficiency Anemia, Lipid Profile, Dyslipidemia, Hemoglobin, Serum Ferritin, India
Citation
Aithal Ananya P, Chinmai P M, Chirag P M, M Vinaya Swami P, Manjunath Sanath, M Mohanish N. A Study Of Correlation Between Serum Lipid Profile And Iron Deficiency Anemia In Indian Patients. Indian Journal Of Applied Research. 2025 Jul; 15(7): 23-25