Microbiological Screening Of Otorrhoea From People Coming To Hospital In Mahajanga

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dc.contributor.authorRivo, Rakotomalalaen_US
dc.contributor.authorpatrick, Randrianandrainaen_US
dc.contributor.authortsiriniaina, Ramavosonen_US
dc.contributor.authorfiacre, Ramisarimananaen_US
dc.contributor.authorainamalala, Catherine Razafindrakotoen_US
dc.contributor.authortahirimalala, Rabenandrianinaen_US
dc.contributor.authorDavidra, Rajaonatahianaen_US
dc.contributor.authorodilon, Tiandazaen_US
dc.contributor.authorolivat, Rakoto Alsonen_US
dc.contributor.authorandry, Rasamindrakotrokaen_US
dc.contributor.authorrasoamialy, Razanakolonaen_US
dc.date.accessioned2020-05-05T07:06:58Z
dc.date.available2020-05-05T07:06:58Z
dc.date.issued2020-01
dc.description.abstractBackground: Otorrhoea commonly hits young people. Ciprofloxacin and rifampicin are the two ear drop antibiotics commonly used for the probabilistic treatmentof otitis in Madagascar. This study aimedto determine the potentially dangerous bacteria involved in otitis and to identify their resistance to fluoroquinolone or rifampicin. Method: A pro-spective study was conducted with the collaboration ofthe Ear Nose and Throat unit (ENT) at the laboratory of UHC PZaGa in Mahajanga. In whole, 56 patients were included. Samplings of otorrhoeawere performed by aspirating the auditory canal using 2ml sterile syringeand then were headed to thelaboratory in less than 30 minutes for analysis. Results:Amidst identified microorganisms were fungus (4,7%) and bacteria (95,3%) to which Gram-negative bacilli represented72.1% (n=44), Gram-positive cocci 6.4% (n=10), Gram-positive bacilli 8.2% (n=5) and Gram-negative cocci 3.3% (n=2). Amongthese bacterias, Pseudomonas aeruginosa and Proteus sp were predominant, with respec-tively 41% (n=25), 23% (n=14). However,three casesof S. aureusreported six with negative coagulaseStaphylococ-cus, one with Escherichia coli, one with Klebsiella sp, one with Haemophilus sp, two cases with Neisseria sp and four cases with Corynebacterium sp. Two types of cultures were noticed, one of them monomorphic (91.1%, n=51) and the other polymorphic (8.9%, n=5) to which three associations of P. aeruginosa-Proteus sp, 1 association of P. aerugino-sa-coagulase-negative Staphylococcus and one association of P. aeruginosa-E. coli. No resistance to ciprofloxacin was observed with Pseudomonas, Neisseria sp, Haemophilus, and enterobacteria except for E. coli. No resistance to rifampicin was observed with S. aureus. However, the sensitivity of S. aureus to ciprofloxacin decreased(one bacte-rium out of three). Conclusion:The use of rifampicin or fluoroquinolones should be based on the type of ear infec-tions. Rifampicin is suggested only if S. aureuswas responsible for otitis. Ciprofloxacin use is still yet sensible to Gram-negative bacilli.en_US
dc.identifier.affiliationsLaboratory of University Hospital Center PZAGA, University of Mahajanga , Madagascar,en_US
dc.identifier.affiliationsENT Unit, University Hospital Center PZAGA, University of Mahajanga, Madagascaren_US
dc.identifier.affiliationsLaboratory of University Hospital Center Morafeno, TUniversity of Toamasina, Madagascar,en_US
dc.identifier.affiliationsFaculty of Medecine, University of Mahajanga, Madagascar,en_US
dc.identifier.affiliationsFaculty of Medecine, University of Antananarivo, Madagascar.en_US
dc.identifier.citationRivo Rakotomalala, Patrick Randrianandraina, Tsiriniaina Ramavoson, Fiacre Ramisarimanana, Ainamalala Catherine Razafindrakoto, Tahirimalala Rabenandrianina, Davidra Rajaonatahiana, Odilon Tiandaza, Olivat Rakoto Alson, Andry Rasamindrakotroka, Rasoamialy Razanakolona. Microbiological Screening Of Otorrhoea From People Coming To Hospital In Mahajanga . International Journal of Clinical and Biomedical Research. 2020 Jan; 6(1): 25-28en_US
dc.identifier.issn2395-0471
dc.identifier.issn2521-0394
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/200884
dc.languageenen_US
dc.publisherSumathi Publicationsen_US
dc.relation.issuenumber1en_US
dc.relation.volume6en_US
dc.source.urihttps://www.doi.org/10.31878/ijcbr.2019.61.07en_US
dc.subjectOtitisen_US
dc.subjectBacteriaen_US
dc.subjectRifampicinen_US
dc.subjectCiprofloxacin.en_US
dc.titleMicrobiological Screening Of Otorrhoea From People Coming To Hospital In Mahajangaen_US
dc.typeJournal Articleen_US
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