The phytochemical and chemotaxonomic study of Salvia spp. growing in Ukraine

Simple item page
dc.contributor.authorKoshovyi, Olehen_US
dc.contributor.authorAin, Raalen_US
dc.contributor.authorAlla, Kovalevaen_US
dc.contributor.authorMykhailo, Myhaen_US
dc.contributor.authorTetyana, Ilinaen_US
dc.contributor.authorNatalia, Borodinaen_US
dc.contributor.authorAndrey, Komissarenkoen_US
dc.date.accessioned2020-10-16T08:50:35Z
dc.date.available2020-10-16T08:50:35Z
dc.date.issued2020-05
dc.description.abstractSalvia officinalis is a well-studied and popular medicinal plant containing toxic thujones, rather limitedphytochemical and pharmacological studies have been performed on other Salvia spp. The aim of the studywas to perform phytochemical and chemotaxonomic studies of Salvia genus species (n = 16) from Ukraineto identify the most promising species for the pharmaceutical industry. The content of essential oils from theleaves of 16 Salvia spp. has been studied by gas chromatography/mass spectrometry (MS) and polyphenols byhigh performance liquid chromatography/MS, and a chemotaxonomic study has been performed by calculationof coefficients of occurrence, originality, and pair affinity. The Salvia spp. is characterized by the presence ofmonoterpenoids, hydroxycinnamic acids – derivatives of caffeic acid, and flavonoids – derivatives of luteolinand apigenin. The highest content of essential oil is observed in the leaves of S. officinalis, S. grandiflora, andS. scabiosifolia (1.41%–1.85%). The highest amount of hydroxycinnamic acids is in the leaves of S. pratensis,S. illuminata, S. austriaca, and S. verticillata; the highest content of flavonoids and phenolic compounds isfound in the leaves of S. grandiflora, S. pratensis, S. illuminata, S. nemorosa, S. pendula, S. sylvestris, S.nutans, S. verticillata, and S. cernua. The chemical profile of the genus has been determined; it is characterizedby terpenoids such as α- and β-pinene, camphane derivatives (camphene, camphor, and borneol), p-cymene,1,8-cineol, limonene, phenolic compounds (caffeic and rosmarinic acids), and flavonoids (cynaroside,cosmosiin, hispidulin, and cirsimaritin). A rather high concentration of toxic _- and _-thujone is typical onlyin the essential oil of S. officinalis (33.6% and 6.5%, respectively). The most promising species for use in thepharmaceutical industry are S. grandiflora, S. cernua, S.pratensis, S. nemorosa, and S. verticillata.en_US
dc.identifier.affiliationsPharmacognosy Department, The National University of Pharmacy, Pushkinska st 53, 61002 Kharkiv, Ukraineen_US
dc.identifier.affiliationsInstitute of Pharmacy, Faculty of Pharmacy, University of Tartu, Nooruse 1, 50411 Tartu, Estoniaen_US
dc.identifier.affiliationsPharmacognosy Department, The National University of Pharmacy, Pushkinska st 53, 61002 Kharkiv, Ukraine.en_US
dc.identifier.affiliationsPharmacognosy Department, The National University of Pharmacy, Pushkinska st 53, 61002 Kharkiv, Ukraine.en_US
dc.identifier.affiliationsPharmacognosy Department, The National University of Pharmacy, Pushkinska st 53, 61002 Kharkiv, Ukraine.en_US
dc.identifier.affiliationsPharmacognosy Department, The National University of Pharmacy, Pushkinska st 53, 61002 Kharkiv, Ukraine.en_US
dc.identifier.affiliationsPharmacognosy Department, The National University of Pharmacy, Pushkinska st 53, 61002 Kharkiv, Ukraine.en_US
dc.identifier.citationKoshovyi Oleh, Ain Raal, Alla Kovaleva, Mykhailo Myha, Tetyana Ilina, Natalia Borodina, Andrey Komissarenko. The phytochemical and chemotaxonomic study of Salvia spp. growing in Ukraine. Journal of Applied Biology & Biotechnology. 2020 May; 2020 May: 29-36en_US
dc.identifier.issn2455-7005
dc.identifier.issn2347-212X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/209902
dc.languageenen_US
dc.publisherOpen Science Publishers LLPen_US
dc.relation.issuenumber3en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org//10.7324/JABB.2020.80306en_US
dc.subjectSageen_US
dc.subjectchemotaxonomyen_US
dc.subjectterpenoidsen_US
dc.subjectpolyphenolsen_US
dc.subjectgas chromatographyen_US
dc.subjectHPLC.en_US
dc.titleThe phytochemical and chemotaxonomic study of Salvia spp. growing in Ukraineen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
jabb2020v8n3p29.pdf
Size:
1.21 MB
Format:
Adobe Portable Document Format
Download
Collections
Journal of Applied Biology & Biotechnology