Report of an Unusual Case of Hemosiderotic Fibrohistiocytic Lipomatous Tumor with Systematic Review of Clinicopathological Characteristics and Differential Diagnosis

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dc.contributor.authorSoumya, BMen_US
dc.contributor.authorSharma, Len_US
dc.contributor.authorKulkarni, Ven_US
dc.contributor.authorPreethi, CR.en_US
dc.date.accessioned2024-12-02T07:35:14Z
dc.date.available2024-12-02T07:35:14Z
dc.date.issued2023-01
dc.description.abstractThe spectrum of lipomatous lesions ranges from benign to highly malignant disease. Differentiation between these mesenchymal lesions is important for pathologist as well as clinician to indicate prognosis and choose the most appropriate treatment. Hemosiderotic firohistiocytic lipomatous tumor (HFLT) is a rare subtype of lipomatous tumor. The diagnosis is usually based on clinical, histological, and immunohistochemical (IHC) information. We reported a case of 56 years old man with a painful mass in the dorsal aspect of the thigh showing an unusal clinical presentation but a characteristic histological and IHC features. In this article we have retrospectively reviewed the 67 cases of HFLT reported in literature so far along with one case reported at our institution. The review focuses on clinicopathological and histomorphological characteristics of HFLT and the related entities. The hallmark of HFLT and its related lesions is complex admixture of mature adipose tissue, spindle tumor cells with striking deposition of hemosiderin pigment. Even though HFLT shows marked predeliction for the distal extremeties especially the foot/ ankle with a female preponderance, they can occur at uncommon site such as thigh and also in males as seen in our case.en_US
dc.identifier.affiliationsAssociate Professor of Pathology, Department of Pathology, JJM Medical College, Davangere, Karnataka, Indiaen_US
dc.identifier.affiliationsPostgraduate of Pathology, Department of Pathology, JJM Medical College, Davangere, Karnataka, Indiaen_US
dc.identifier.affiliationsProfessor and Head, Department of Pathology, JJM Medical College, Davangere, Karnataka, Indiaen_US
dc.identifier.affiliationsProfessor of Pathology, Department of Pathology, JJM Medical College, Davangere, Karnataka, Indiaen_US
dc.identifier.citationSoumya BM, Sharma L, Kulkarni V, Preethi CR. . Report of an Unusual Case of Hemosiderotic Fibrohistiocytic Lipomatous Tumor with Systematic Review of Clinicopathological Characteristics and Differential Diagnosis. Journal of Medical Sciences and Health. 2023 Jan; 9(1): 110-117en_US
dc.identifier.issn2394-9481
dc.identifier.issn2394-949X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/239191
dc.languageenen_US
dc.publisherAdichunchunagiri Institute of Medical Sciencesen_US
dc.relation.issuenumber1en_US
dc.relation.volume9en_US
dc.source.urihttps://doi.org/10.46347/jmsh.v9i1.22.492en_US
dc.subjectPleomorphic hyalinizing angiectatic tumoren_US
dc.subjectHemosiderotic fibrolipomatous tumoren_US
dc.subjectMyxoinflammatory Fibroblastic Sarcomaen_US
dc.subjectHemosiderinen_US
dc.subjectLipomaen_US
dc.titleReport of an Unusual Case of Hemosiderotic Fibrohistiocytic Lipomatous Tumor with Systematic Review of Clinicopathological Characteristics and Differential Diagnosisen_US
dc.typeJournal Articleen_US
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