Histopathological Patterns of Gastric Mucosal Biopsies in Dyspepsia – A Study of 550 Cases

Simple item page
dc.contributor.authorSuman, Ken_US
dc.contributor.authorRao, Namrataen_US
dc.date.accessioned2020-11-18T10:27:23Z
dc.date.available2020-11-18T10:27:23Z
dc.date.issued2019-09
dc.description.abstractObjective: Dyspepsia is a common condition which is seen in the medical outpatient department. Helicobacter pylori is the causal agent in most of the cases of gastritis and peptic ulceration. This is a retrospective study aimed to study the histological patterns in gastric biopsy from patients with complaints of dyspepsia.Methods: In this study, a total of 550 biopsy samples from patients with a clinical history of dyspepsia which were received at the department of histopathology were analyzed. The biopsy samples were procured in Bouin’s fixative and were paraffin embedded. Sections were taken and stained with hematoxylin and eosin. May-Grunwald-Giemsa stain was used to visualize H. pylori. Alcian blue stain was used to identify intestinal metaplasia.Results: It was observed that 194 (35.2%) cases showed features of chronic gastritis without H. pylori infection. H. pylori was noted in a total of 296 cases (53.8%) among which 256 cases (46.5%) showed features of chronic gastritis, 28 cases (5.09%) showed active gastritis, and 12 cases (2.2%) showed features of chronic gastritis with intestinal metaplasia.Conclusions: Chronic gastritis is a common condition worldwide. Chronic infection with H. pylori accounts for the majority of cases of chronic gastritis.en_US
dc.identifier.affiliationsAssistant Professor, Department of Pathology, Melaka Manipal Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India*en_US
dc.identifier.citationSuman K, Rao Namrata. Histopathological Patterns of Gastric Mucosal Biopsies in Dyspepsia – A Study of 550 Cases. Journal of Medical Sciences and Health. 2019 Sep; 5(3): 1-6en_US
dc.identifier.issn2394-9481
dc.identifier.issn2394-949X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/215693
dc.languageenen_US
dc.publisherAdichunchunagiri Institute of Medical Sciencesen_US
dc.relation.issuenumber3en_US
dc.relation.volume5en_US
dc.source.urihttps://doi.org/10.46347/jmsh.2019.v05i03.001en_US
dc.subjectActivityen_US
dc.subjectdyspepsiaen_US
dc.subjectgastritisen_US
dc.subjectHelicobacter pylorien_US
dc.subjectinflammationen_US
dc.subjectmetaplasia.en_US
dc.titleHistopathological Patterns of Gastric Mucosal Biopsies in Dyspepsia – A Study of 550 Casesen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
jmsh2019v5n3p1.pdf
Size:
2.48 MB
Format:
Adobe Portable Document Format
Download
Collections
Journal of Medical Sciences and Health