Hematoporphyrin derivative binding and photosensitization in human glioblastoma cells: comparison of exponential and plateau phase cells.

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dc.contributor.authorSreenivasan, Ren_US
dc.contributor.authorJoshi, P Gen_US
dc.contributor.authorJoshi, N Ben_US
dc.date.accessioned2009-05-28T12:35:21Z
dc.date.available2009-05-28T12:35:21Z
dc.date.issued1994-11-01en_US
dc.description.abstractPlateau phase glioblastoma (U 87MG) cells were found more photosensitive than the exponentially growing cells. In both phases of growth, the photosensitivity showed further enhancement on incubating the cells with HpD for longer duration. Plateau phase cells accumulated more HpD than exponential phase cells for shorter duration of incubation with HpD, however, for longer duration of incubation, the amount of drug uptake was almost the same in both phases of growth. Fluorescence spectra of cell bound HpD showed a difference in spectral intensity distribution in exponential and plateau phase cells. In exponential phase cells, the fluorescence maximum of cell bound HpD was at 615 nm whereas in plateau phase cells the same was at 636 nm.en_US
dc.description.affiliationDepartment of Biophysics, National Institute of Mental Health and Neuro Science, Bangalore, India.en_US
dc.identifier.citationSreenivasan R, Joshi PG, Joshi NB. Hematoporphyrin derivative binding and photosensitization in human glioblastoma cells: comparison of exponential and plateau phase cells. Indian Journal of Experimental Biology. 1994 Nov; 32(11): 763-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/58286
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshBrain Neoplasms --metabolismen_US
dc.subject.meshCell Cycle --physiologyen_US
dc.subject.meshGlioblastoma --metabolismen_US
dc.subject.meshHematoporphyrin Derivative --metabolismen_US
dc.subject.meshHumansen_US
dc.titleHematoporphyrin derivative binding and photosensitization in human glioblastoma cells: comparison of exponential and plateau phase cells.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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