Phenolic Content and Enzyme Inhibition Activities Barbarea auriculata var. paludosa, B. integrifolia and B. plantaginea (Brassicaceae)'s

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dc.contributor.authorBadem, Merveen_US
dc.contributor.authorSener, Sıla Ozlemen_US
dc.contributor.authorKorkmaz, Nuriyeen_US
dc.contributor.authorKanbolat, Seydaen_US
dc.contributor.authorYildirmiş, Sermeten_US
dc.contributor.authorOzgen, Ufuken_US
dc.contributor.authorAliyazicioglu, Rezzanen_US
dc.contributor.authorKandemir, Alien_US
dc.date.accessioned2020-11-18T10:30:09Z
dc.date.available2020-11-18T10:30:09Z
dc.date.issued2020-06
dc.description.abstractBarbareagenus has been presented about 12 species, 9 taxon are endemic, in Turkey. In this sudy, enzyme inhibition was carried out on methanolic extract, chloroform extract, ethyl acetate extract, and the remaining aqueous phases from the aerial parts of B. auriculata var paludosa, B. integrifolia, andB. plantagineaspecies and HPLC studies were carried on their methanolic extract in the present study for the first time. Phenolic compounds were determined using reverse phase-high performance liquid chromatography (RP-HPLC). p-OH benzoic acid, vanilic acid, syringaldehyde, coumaric acid, synapic acid and benzoic acid were detected as major phenolic compounds in the species. Assay of enzyme inhibition activitieswere done using spectrophotometric methods. Results of these studies reveal that the extracts from these species have moderate tyrosinase, AChE and BuChE inhibitory activity. In the biological activity studies, it was observed that B. integrifoliawas thehighest activityen_US
dc.identifier.affiliationsDepartment of Biochemistry, Faculty of Pharmacy, Karadeniz Technical University, 61080,Trabzon, Turkeyen_US
dc.identifier.affiliationsDepartment of Pharmacognosy, Faculty of Pharmacy, Karadeniz Technical University, 61080,Trabzon, Turkeyen_US
dc.identifier.affiliationsDepartment of Biochemistry, Faculty of Pharmacy, Karadeniz Technical University, 61080,Trabzon, Turkeyen_US
dc.identifier.affiliationsDepartment of Biochemistry, Faculty of Pharmacy, Karadeniz Technical University, 61080,Trabzon, Turkeyen_US
dc.identifier.affiliationsDepartment of Biochemistry, Faculty of Pharmacy, Karadeniz Technical University, 61080,Trabzon, Turkeyen_US
dc.identifier.affiliationsDepartment of Biology, Faculty of Science, Erzincan University, 24000,Erzincan, Turkeyen_US
dc.identifier.citationBadem Merve, Sener Sıla Ozlem, Korkmaz Nuriye, Kanbolat Seyda, Yildirmiş Sermet, Ozgen Ufuk, Aliyazicioglu Rezzan, Kandemir Ali. Phenolic Content and Enzyme Inhibition Activities Barbarea auriculata var. paludosa, B. integrifolia and B. plantaginea (Brassicaceae)'s. Journal of Pharmaceutical Research International. 2020 Jun; 32(9): 86-93en_US
dc.identifier.issn2456-9119
dc.identifier.issn2231-2919
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/215764
dc.languageenen_US
dc.publisherSCIENCEDOMAIN internationalen_US
dc.relation.issuenumber9en_US
dc.relation.volume32en_US
dc.source.urihttps://doi.org/10.9734/JPRI/2020/v32i930486en_US
dc.subjectBarbareaen_US
dc.subjectbrassicaceaeen_US
dc.subjectenzyme ınhibitionen_US
dc.subjectphytochemicalen_US
dc.titlePhenolic Content and Enzyme Inhibition Activities Barbarea auriculata var. paludosa, B. integrifolia and B. plantaginea (Brassicaceae)'sen_US
dc.typeJournal Articleen_US
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