Effect Of TXA On Intraoperative Blood Loss In Mandibular Fracture Surgeries A Prospective, Double Blinded Randomized Clinical Trial

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dc.contributor.authorKhan, Zen_US
dc.contributor.authorPatel, Den_US
dc.contributor.authorRai, Ben_US
dc.contributor.authorGohil, Men_US
dc.contributor.authorMishra, Men_US
dc.contributor.authorParekh, P.en_US
dc.date.accessioned2023-07-14T08:16:05Z
dc.date.available2023-07-14T08:16:05Z
dc.date.issued2021-11
dc.description.abstractBackground:The aim of this doubleblind prospective study was to determine whether administering 1 gm Tranexamic Acid (TXA) would the intraoperative blood loss during the Open Reduction and Internal Fixation (ORIF) surgery of mandibular fracture via the intraoral approach operated under local anesthesia (LA).Material And Methods:20 patients who underwent ORIF surgery ofmandibular fractures under LA were randomly allocated to two groups. Study group was administered 1 gm TXA diluted in a 500 ml Ringer Lactate solution one hour before thesurgery. Control group did not receive any such IV infusion. All the surgeries were performed by the same surgeon.Result:Mean difference in Intraoperative blood loss between the two groups was found out to be statistically insignificant. Effect of age, gender or site of fracture was also found out to be insignificant. Conclusion:There is not much effect of TXA on intraoperative blood loss during ORIF of a mandibular fracture via the intraoral approach. Even without tranexamic, if area is infiltrated with adrenaline, proper flap reflection and tissue handling technique is used, and vital structures avoided; blood loss will be minimal.en_US
dc.identifier.affiliationsReader, Pacific Dental CollegeAnd Hospital, Udaipuren_US
dc.identifier.affiliationsAssistant Professor, Ananta Institute Of Medical Sciences, Udaipuren_US
dc.identifier.affiliationsProfessor, Pacific Dental CollegeAnd Hospital, Udaipuren_US
dc.identifier.affiliationsReaderen_US
dc.identifier.affiliations*Senior Lecturer, College Of Dental Sciences Amargadh, Bhavnagaren_US
dc.identifier.affiliationsSenior Lecturer, Geetanjali Dental And Research Institute, Udaipuren_US
dc.identifier.citationKhan Z, Patel D, Rai B, Gohil M, Mishra M, Parekh P.. Effect Of TXA On Intraoperative Blood Loss In Mandibular Fracture Surgeries A Prospective, Double Blinded Randomized Clinical Trial . National Journal of Integrated Research in Medicine. 2021 Nov; 12(5): 36-41en_US
dc.identifier.issn0975-9840
dc.identifier.issn2230 - 9969
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/219806
dc.languageenen_US
dc.publisherAssociation of Health Professionals and Health Educatorsen_US
dc.relation.issuenumber5en_US
dc.relation.volume12en_US
dc.source.urihttps://nicpd.ac.in/ojs-/index.php/njirm/article/view/3180en_US
dc.subjectMandibular fracturesen_US
dc.subjectTranexamic Aciden_US
dc.subjectOpen reduction and internalfixationen_US
dc.subjectBlood lossen_US
dc.titleEffect Of TXA On Intraoperative Blood Loss In Mandibular Fracture Surgeries A Prospective, Double Blinded Randomized Clinical Trialen_US
dc.typeJournal Articleen_US
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