Sweet’s syndrome.
Loading...
Date
2014-05
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Acute febrile neutrophilic dermatosis or Sweet’s syndrome (SS) is characterized by painful,
erythematous plaques of rapid onset accompanied by fever. The etiology of SS is unknown and
it may be associated with antecedent infections, malignancies, autoimmune diseases, drugs and
vaccines, upper respiratory or gastrointestinal infection, pregnancy, inflammatory bowel disease
as well as chemotherapy or idiopathic. The standard therapy for SS is systemic corticosteroids.
We report a rare case of 19‑year‑old young male patient with complaint of severe ill‑defined
type of pain in both jaws associated with plaques and papules on extensor surfaces of upper
and lower extremities with bodyache and myalgia. Histopathological examination suggested
perivascular neutrophilic infiltration with scattered eosinophils. Sweet syndrome has rare oral
manifestations secondary to hematological changes. It can also present as a paraneoplastic
syndrome (malignancy‑associated form of condition, which is most commonly related to acute
myelogenous leukemia), which leads to poor prognosis and thus it requires careful examination,
early diagnosis and long‑term follow‑up.
Description
Keywords
Corticosteroids, cutaneous eruption, granulocyte macrophage – colony stimulating, neutrophilic dermatosis, Sweet’s syndrome
Citation
Limdiwala Piyush G, Parikh Shilpa J, Shah Jigna S. Sweet’s syndrome. Indian Journal of Dental Research. 2014 May-Jun; 25(3): 401-405.