Formulation and In Vitro Evaluation of Gabapentin Controlled Release Tablets Using Natural Polymers

Simple item page
dc.contributor.authorSruthi, Ven_US
dc.contributor.authorAlagarsamy, Ven_US
dc.contributor.authorBose, P. Subhash Chandraen_US
dc.contributor.authorSaritha, Den_US
dc.contributor.authorReddy, P. Srikanthen_US
dc.date.accessioned2025-08-13T11:15:53Z
dc.date.available2025-08-13T11:15:53Z
dc.date.issued2025-06
dc.description.abstractThis research set out to find the best way to use various grades of controlled-release polymer. To create a new one that would be just as effective as the original, but cheaper, and of better quality. The dosage form was designed using Hydroxypropyl Methyl Cellulose (HPMC K15MCR) as matrix builders. Research on the compatibility of medication and polymer was carried out. The flowability of the powder blend was optimized after studying the blend. Uniformity Compressing free-flowing powder directly into tablet form was the method of choice. They were successfully combined with the HPMC, MCC, and DCP networks. In order to compare different dissolution characteristics, we also presented the mean dissolving time. Clinical trials have shown that controlled-release gabapentin tablets are formulated by direct compression outperforms its immediate-release counterparts in terms of therapeutic efficacy.en_US
dc.identifier.affiliationsDepartment of Pharmacognosy, SSJ College of Pharmacy, Vattinagula Pally, Hyderabad, Telangana, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutical Chemistry, MNR College of Pharmacy, Sangareddy, Telangana, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, MNR College of Pharmacy, Sangareddy, Telangana, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, Sultan-ul-Uloom College of Pharmacy, Hyderabad, Telangana, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmaceutics, MNR College of Pharmacy, Sangareddy, Telangana, India.en_US
dc.identifier.citationSruthi V, Alagarsamy V, Bose P. Subhash Chandra, Saritha D, Reddy P. Srikanth . Formulation and In Vitro Evaluation of Gabapentin Controlled Release Tablets Using Natural Polymers . International Journal of Ayurveda and Pharma Research. 2025 Jun; 13(6): 1-10en_US
dc.identifier.issn2322-0902
dc.identifier.issn2322-0910
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/253382
dc.languageenen_US
dc.publisherMahadev Publicationsen_US
dc.relation.issuenumber6en_US
dc.relation.volume13en_US
dc.source.urihttps://doi.org/10.47070/ijapr.v13i6.3748en_US
dc.subjectGabapentinen_US
dc.subjectHPMCen_US
dc.subjectMCC and DCP networken_US
dc.titleFormulation and In Vitro Evaluation of Gabapentin Controlled Release Tablets Using Natural Polymersen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ijapr2025v13n6p1.pdf
Size:
490.93 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Ayurveda and Pharma Research