Evaluation of total soluble solids content (TSSC) and endogenous pH in antimicrobials of pediatric use.

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dc.contributor.authorCavalcanti, Alessandro Leite
dc.contributor.authorOliveira, Klélia Forte de
dc.contributor.authorXavier, Alidianne F C
dc.contributor.authorPinto, Daiane S C
dc.contributor.authorVieira, Fernando Fernandes
dc.date.accessioned2013-10-10T10:10:24Z
dc.date.available2013-10-10T10:10:24Z
dc.date.issued2013-07
dc.description.abstractBackground: The use of liquid pharmaceutical preparations is a daily occurrence for some children. Evidences show a significant relation between the intake of oral sucrose based medicines and an increase incidence in dental caries. Aim: This in vitro experimental study evaluated the Total Soluble Solids Content (TSSC) by means of Brix scale refractometry and the endogenous pH of antimicrobials of pediatric use presented as oral suspensions. Materials and Methods: Nine medications (6 chemotherapics and 3 antibiotics) were evaluated by random experiment with 3 repetitions for each sample. The analysis of TSSC readings were performed by Brix refractometry using the Abbé refractometer, and the pH values were determined by potentiometry. Results: The mean TSS contents ranged from 11.73 (Keflaxina) to 63.83 (Azitromed). The minimum and maximum mean pH values were 4.12 (Keflaxina) and 10.97 (Zitroneo), respectively. Conclusions: The chemotherapic antimicrobials evaluated in this study presented the highest TSSC means, while the antibiotics showed pHs below the values considered as critical, which may contribute to the development of caries lesions in case of inadequate administration of these medications to children.en_US
dc.identifier.citationCavalcanti Alessandro Leite, Oliveira Klélia Forte de, Xavier Alidianne F C, Pinto Daiane S C, Vieira Fernando Fernandes. Evaluation of total soluble solids content (TSSC) and endogenous pH in antimicrobials of pediatric use. Indian Journal of Dental Research. 2013 Jul-Aug; 24(4): 498-501.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/148739
dc.language.isoenen_US
dc.source.urihttps://www.ijdr.in/article.asp?issn=0970-9290;year=2013;volume=24;issue=4;spage=498;epage=501;aulast=Cavalcantien_US
dc.subjectAdministrationen_US
dc.subjectoralen_US
dc.subjectpediatricsen_US
dc.subjectpharmaceutical preparationsen_US
dc.subjecttotal solidsen_US
dc.titleEvaluation of total soluble solids content (TSSC) and endogenous pH in antimicrobials of pediatric use.en_US
dc.typeArticleen_US
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