Drug utilization study of urinary tract infections in obstetrics and gynecology department

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dc.contributor.authorGupta, A.en_US
dc.contributor.authorAgarwal, C.en_US
dc.contributor.authorBhatti, K.en_US
dc.contributor.authorAgarwal, A.en_US
dc.contributor.authorTayal, Ren_US
dc.date.accessioned2024-09-24T06:10:55Z
dc.date.available2024-09-24T06:10:55Z
dc.date.issued2023-06
dc.description.abstractBackground: The aim of study was to determine the utilization pattern of antimicrobial agents in obstetrics and gynaecology department. Antimicrobial agents are one of the most commonly used drugs word wide and has main contribution in human health system. UTI infection is one of the most widespread bacterial infections of genitourinary tract which can be treated by AMAs. The main aim of this study is; to identify the pattern of drug utilisation of antimicrobials in prescriptions, to analyse the utilisation of different classes of drugs and to identify the outcome of the treatment. Methods: This prospective, observational and analytical study was conducted in patients of obstetrics and gynaecology department of MMIMSR, Mullana after obtaining approval from institutional ethical committee. Demographic data, medical history, prescribed treatment details (drug name, dose, frequency, dosage form etc) and diagnosis, type of UTI, laboratory investigations and outcome of treatment was evaluated. Results: A total 242 female patients were registered, out of which 200 were included in the study as 42 were dropouts. Majority of female patients were belonging to the age group of 18-37 (63%). Most of the female patients had uncomplicated UTI 188 (94%) (p value=0.35), 186 (93%) had significant pyuria and 64 (32%) had urine culture positive (p value= 0.01). Burning micturation and frequency were the most common symptoms observed in 146 (73%). In the study 67(33.5%) females were pregnant and 133 (66.5%) were non pregnant (p value= 0.01). Out of 200 patients 64 (32%) had positive urine cultures and 136 (68%) had negative urine culture reports. E. coli 28 (14%) was the most common bacteria isolated followed by Klebsiella 16 (8%). Average number of drugs prescribed per prescription to non-pregnant was 3.97 and to pregnant were 4.67. In majority of prescriptions, the drugs were prescribed by oral routes (51%) and most of the drugs prescribed were generic (57%). Most of the patients (93%) were recovered from UTIs in 5-7 days of treatment. Conclusions: Our study concluded that the uses of AMAs for UTI were found to be rational and according to the causative organism and susceptibility pattern.en_US
dc.identifier.affiliationsDepartment of Pharmacology, MMIMSR, MMDU, Mullana, Ambala, Haryana, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, MMIMSR, MMDU, Mullana, Ambala, Haryana, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, MMIMSR, MMDU, Mullana, Ambala, Haryana, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, MMIMSR, MMDU, Mullana, Ambala, Haryana, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, MMIMSR, MMDU, Mullana, Ambala, Haryana, Indiaen_US
dc.identifier.citationGupta A., Agarwal C., Bhatti K., Agarwal A., Tayal R. Drug utilization study of urinary tract infections in obstetrics and gynecology department. International Journal of Basic & Clinical Pharmacology. 2023 May; 12(3): 476-480en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/226664
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber3en_US
dc.relation.volume12en_US
dc.source.urihttps://doi.org/10.18203/2319-2003.ijbcp20231131en_US
dc.subjectDrug utilizationen_US
dc.subjectUrinary tract infectionen_US
dc.subjectAntimicrobial agentsen_US
dc.subjectObstetrics and gynaecology departmenten_US
dc.titleDrug utilization study of urinary tract infections in obstetrics and gynecology departmenten_US
dc.typeJournal Articleen_US
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