Evaluation of antibiotic utilization pattern in indoor patients of obstetrics and gynaecology in a tertiary care hospital of central India

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dc.contributor.authorKumawat, Sen_US
dc.contributor.authorDudhgaonkar, Sen_US
dc.contributor.authorUike, Pen_US
dc.date.accessioned2025-06-18T11:23:09Z
dc.date.available2025-06-18T11:23:09Z
dc.date.issued2025-06
dc.description.abstractBackground: Understanding prescribing patterns is vital to address irrational antibiotic use, a key contributor to antimicrobial resistance. The aim of the study was to evaluate antibiotic prescription practices among hospitalized patients and examine the presence of an antibiotic stewardship program in a tertiary care hospital. The findings may aid in developing stewardship initiatives to promote rational antibiotic use. Methods: A prospective observational study was conducted from March 1 to August 30, 2024, at Government Medical College and Hospital, Gondia, Maharashtra. Data were collected using WHO prescribing drug indicators and analysed using SPSS Version 25. Results: The mean difference in final and initial serum creatinine values were observed to be 0.32 and 0.52 with a standard deviation of 0.228 and 0.387 in AM and GM group respectively. This difference was statistically significant with p value of 0.007. The mean difference in final and initial creatinine clearance values were observed to be 18.82 and 24.76 with a standard deviation of 10.14 and 11.93 in AM and GM group respectively. This difference was also statistically significant with p value of 0.013. Nephrotoxicity occurred in 9 out of 50 patients (18%) in AM group out of which 12% were male and 6% were female whereas in case of GM group nephrotoxicity occurred in 16 out of 50 patients (32%) in which 26% were male and 6% were female. Conclusions: Prescribing patterns deviated from WHO indicators, with high empirical use. Strengthening antimicrobial stewardship and increasing microbiological testing are essential to improve antibiotic practices.en_US
dc.identifier.affiliationsDepartment of Pharmacology, Government Medical College, Gondia, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, Government Medical College, Gondia, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, Government Medical College, Gondia, Maharashtra, Indiaen_US
dc.identifier.citationKumawat S, Dudhgaonkar S, Uike P. Evaluation of antibiotic utilization pattern in indoor patients of obstetrics and gynaecology in a tertiary care hospital of central India. International Journal of Basic & Clinical Pharmacology. 2025 Jun; 14(3): 345-351en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/248634
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber3en_US
dc.relation.volume14en_US
dc.source.urihttps://doi.org/10.18203/2319-2003.ijbcp20251058en_US
dc.subjectWHO-DUIen_US
dc.subjectPrescribing patternen_US
dc.subjectAntibiotic Stewardship Programen_US
dc.subjectIndiaen_US
dc.titleEvaluation of antibiotic utilization pattern in indoor patients of obstetrics and gynaecology in a tertiary care hospital of central Indiaen_US
dc.typeJournal Articleen_US
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