Retinal Nerve Fiber Layer and Visual Field Assessment in Primary Open Angle Glaucoma – a Detailed Cross-sectional Examination
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Date
2024-07
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Publisher
FORUM: Fraternity of national Research & pUblication Society of Medical sciences
Abstract
Aims and objectives: This study aims to comprehensively investigate the relationship between visual field impairments and Retinal Nerve Fiber Layer (RNFL) thickness across all stages of primary open-angle glaucoma (POAG). Methods” A cross-sectional observational study was conducted on primary open-angle glaucoma (POAG) patients attending a tertiary eye center in western India. Patients were categorized into groups based on Hodapp, Parrish, and Anderson’s criteria. 52 eyes (26 patients) with POAG were included in the study, comprising 26 (50%) right eyes and 26 (50%) left eyes. Result :The average age of patients in the early, moderate, and severe groups was 50.41 ± 17.06 years, 63.90 ± 8.65 years, and 59.75 ± 7.15 years, respectively. RNFL thickness was compared among early, moderate, and severe POAG cases, revealing values of 86.48 ± 9.15, 70.57 ± 8.65, and 52.93 ± 12.43, respectively. VF indices were also compared, with mean deviation (MD) values of -2.65 ± 1.29, -8.25 ± 1.87, and - 19.45±4.30 for early, moderate, and severe cases, respectively. Significant correlations were observed between structural (superior, inferior, average RNFL thickness) and functional (VF MD) changes, while nasal and temporal RNFL thickness and MD exhibited moderate correlation. Conclusion: This study demonstrated the important role of optical coherence tomography in the early detection of lost RNFL thickness in glaucoma by establishing a correlation between structure and changes, especially RNFL thickness and visual function. This finding not only improves our understanding of the development of glaucoma but also suggests the use of OCT and perimetry as important tools in clinical management
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Keywords
OCT, VF, RNFL
Citation
Asal Shyam, Ghatad Hiren, Lakum Prayosha, Rajatiya Yash. Retinal Nerve Fiber Layer and Visual Field Assessment in Primary Open Angle Glaucoma – a Detailed Cross-sectional Examination. Indian Journal of Applied Basic Medical Sciences. 2024 Jul; 26B(2): 1-8