Interaction of muscle relaxant effect of gallamine with ethanol: in vivo mammalian model.

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dc.contributor.authorKela, A Ken_US
dc.contributor.authorSharma, A Ken_US
dc.contributor.authorMehta, S Cen_US
dc.contributor.authorMehta, V Len_US
dc.date.accessioned2009-05-28T14:38:04Z
dc.date.available2009-05-28T14:38:04Z
dc.date.issued1997-03-01en_US
dc.description.abstractEthanol produces alterations in muscular contraction and neuromuscular function both in vitro and in vivo in mammalian and amphibian tissues in dose dependent manner. It is not very well known whether gallamine, a commonly used muscle relaxant produces any interaction with ethanol. Hence in the present study, interactions of ethanol with gallamine are undertaken using rabbit head drop method. The latency time to produce head drop by gallamine in the absence and presence of ethanol (dose which produce ataxia) was insignificantly different (P > 0.05). It may be due to fact that ataxic dose may not be affecting neuromuscular transmission a significant manner. It, therefore, does not warrant to adjust the dose of gallamine in alcoholic persons.en_US
dc.description.affiliationDepartment of Pharmacology, Lady Hardinge Medical College, New Delhi, India.en_US
dc.identifier.citationKela AK, Sharma AK, Mehta SC, Mehta VL. Interaction of muscle relaxant effect of gallamine with ethanol: in vivo mammalian model. Indian Journal of Experimental Biology. 1997 Mar; 35(3): 302-3en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/60962
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDrug Interactionsen_US
dc.subject.meshEthanol --pharmacologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGallamine Triethiodide --pharmacologyen_US
dc.subject.meshMaleen_US
dc.subject.meshNeuromuscular Nondepolarizing Agents --pharmacologyen_US
dc.subject.meshRabbitsen_US
dc.titleInteraction of muscle relaxant effect of gallamine with ethanol: in vivo mammalian model.en_US
dc.typeJournal Articleen_US
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