Assessment of corneal endothelial cell density and morphology in low and moderate myopic eyes in rural south Indian population

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dc.contributor.authorKumar, N. Sathishen_US
dc.contributor.authorSundararajan, D.en_US
dc.contributor.authorVeluchamy, S.en_US
dc.date.accessioned2019-12-02T10:00:20Z
dc.date.available2019-12-02T10:00:20Z
dc.date.issued2017
dc.description.abstractBackground: Myopia is a common pathologic change of the eye, especially in Asian countries undergoing rapid development. It is known that Asian people have a higher prevalence of myopia. High levels of myopia are associated with increased risk of cataract, posterior vitreous detachment, retinal tears and retinal detachment, increased risk of choroidal neovascularization, and myopic macular degeneration. Aim: To describe the corneal endothelial density and morphology in patients of low and moderate myopic in rural south Indian population and the relationship between endothelial cell parameters and other factors. Materials and Methods: Totally 100 patients were included. Noncontact specular microscopy was performed after taking a history and testing the visual acuity, intraocular pressure measurement, Schirmer’s test and routine eye examination by slit lamp microscope. The studied parameters included mean endothelial cell density (MCD), the coefficient of variation (CV), and percentage of hexagonality. Results: In low myopic eyes the MCD was 2892. 0±146.2/mm2 , the mean CV was 38.4± 0.4 and the mean hexagonal appearance of the cell was 53.9± 0.9%. In moderate myopic eyes, the MCD was 35716± 142.0 mm2 , the mean CV was 37.9± 3.4% and mean the hexagonal appearance of the cell was N. Sathish Kumar, D. Sundararajan, S. Veluchamy. Assessment of corneal endothelial cell density and morphology in low and moderate myopic eyes in rural south Indian population. IAIM, 2017; 4(10): 93-96. Page 94 59.83± 3.6. There were statistically significant differences in MCD (p<0.000) and hexagonal appearance of the cell (p<0.005) between low and moderate myopic eyes. Conclusion: The normative data of the corneal endothelium of eyes indicated that statistically, MCD decreased significantly with age. Previous studies have reported no difference in MCD, the percentage of CV, and percentage of hexagonality between genders. Nevertheless, significantly different percentages of CV between genders were presented in this study.en_US
dc.identifier.affiliationsAssistant Professor, Department Ophthalmology, Meenakshi Medical College, Hospital, and Research Institute, Enathur, Kanchipuram, India, eyesurgeon2004@gmail.comen_US
dc.identifier.affiliationsAssociate Professor, Department Ophthalmology, Meenakshi Medical College, Hospital, and Research Institute, Enathur, Kanchipuram, Indiaen_US
dc.identifier.affiliationsSenior Resident, Department Ophthalmology, Meenakshi Medical College, Hospital, and Research Institute, Enathur, Kanchipuram, Indiaen_US
dc.identifier.citationKumar N. Sathish, Sundararajan D., Veluchamy S.. Assessment of corneal endothelial cell density and morphology in low and moderate myopic eyes in rural south Indian population. International Archives of Integrated Medicine. 2017 Oct; 4(10): 93-96en_US
dc.identifier.issn2394-0026
dc.identifier.issn2394-0034
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/186742
dc.languageenen_US
dc.publisherEducational Society for Excellenceen_US
dc.relation.issuenumber10en_US
dc.relation.volume4en_US
dc.subjectCorneaen_US
dc.subjectMyopic Eyesen_US
dc.subjectSpecular Microscopyen_US
dc.subjectEndothelial Cell Density Morphologyen_US
dc.titleAssessment of corneal endothelial cell density and morphology in low and moderate myopic eyes in rural south Indian populationen_US
dc.typeJournal Articleen_US
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