Estimated creatinine clearance and microalbumin levels for early prediction of nephropathy in adults with diabetes mellitus.
| dc.contributor.author | Tangvarasittichai, Surapon | |
| dc.contributor.author | Tangvarasittichai, Orathai | |
| dc.contributor.author | Meemark, Suwadee | |
| dc.date.accessioned | 2012-01-24T07:35:42Z | |
| dc.date.available | 2012-01-24T07:35:42Z | |
| dc.date.issued | 2009-07 | |
| dc.description.abstract | Objective: To evaluate the association of microalbumin, estimated creatinine clearance (eCrCl), and the other variables in type 2 diabetes (T2D) patients for the prediction of early nephropathy. Methods: Fasting plasma glucose, serum BUN, total cholesterol (TC), triglyceride (TG), HDL-C, serum creatinine, and urine microalbumin were measured with a Hitachi 912 autoanalyzer as microalbumin/gram of creatinine (g CT). The Cockroft-Gault formula was used to calculate the eCrCl and the eCrCl was subdivided as defined by the Kidney Disease Outcome Quality Initiative. Results: In a total of 93 patients, these were 50 patients having T2D and 43 control patients having non-diabetes (NDM). The T2D patients were significantly higher in systolic, diastolic blood pressure, serum creatinine, and urine microalbumin than the NDM patients (P<0.05), and the T2D patients were significantly lower in eCrCl than the NDM patients (P<0.001). The eCrCl was significantly reverse correlated with the duration of abnormal glucose metabolism and age (P<0.05). Conclusion: The eCrCl is important in T2D patients. A decrease in eCrCl with or without an increase in microalbumin excretion may be the universal indication of the presence of diabetic glomerular pathology. | en_US |
| dc.identifier.citation | Tangvarasittichai Surapon, Tangvarasittichai Orathai, Meemark Suwadee. Estimated creatinine clearance and microalbumin levels for early prediction of nephropathy in adults with diabetes mellitus. Siriraj Medical Journal, 2009 Jul; 61(4): 204-210. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/136617 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.sirirajmedj.com/content_download.php?content_id=2452 | en_US |
| dc.subject | Estimated creatinine clearance | en_US |
| dc.subject | Cockroft-Gault | en_US |
| dc.subject | formula | en_US |
| dc.subject | microalbumin | en_US |
| dc.title | Estimated creatinine clearance and microalbumin levels for early prediction of nephropathy in adults with diabetes mellitus. | en_US |
| dc.type | Article | en_US |