Geographical variation in the epidemiology of esophageal cancer in Pakistan.

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dc.contributor.authorBadar, Farhanaen_US
dc.contributor.authorAnwar, Natashaen_US
dc.contributor.authorMahmood, Shahiden_US
dc.date.accessioned2009-05-27T17:42:15Z
dc.date.available2009-05-27T17:42:15Z
dc.date.issued2005-04-17en_US
dc.descriptionAsian Pacific Journal of Cancer Prevention.en_US
dc.description.abstractSTUDY OBJECTIVES: To evaluate whether factors such as the geographic area of residence, sex, and anatomic subsite of esophagus can prognosticate the histologic subtype of esophagus cancer. DESIGN: To study the major histologic subtypes of esophagus cancer stratified by various factors through multivariate analyses using morphology as the dependent factor and gender, province, and subsite of esophagus as independent factors. SETTING: A tertiary care cancer hospital situated in the city of Lahore in Pakistan. PATIENTS: Three hundred and thirty five patients diagnosed either with esophageal squamous cell carcinoma or adenocarcinoma, from December 1994 to April 2004, were included. Subjects were residents of either Punjab or the Northwest Frontier Province in Pakistan. MAIN RESULTS: An excessive likelihood of development of squamous cell carcinoma versus adenocarcinoma was established for the Northwest Frontier Province as compared to Punjab (odds ratio 2.7, 95 percent confidence interval: 1.2, 6.2, p = 0.02), and in the upper-third of the esophagus relative to the lower-third of the organ (odds ratio 8.8, 95 percent confidence interval: 2.8, 28.3, p < 0.001). CONCLUSIONS: This histologic variation may be explained by environmental and lifestyle factors peculiar to geographical regions.en_US
dc.description.affiliationShaukat Khanum Memorial Cancer Hospital and Research Center, 13014 Lahore, Pakistan. farhana@skm.org.pken_US
dc.identifier.citationBadar F, Anwar N, Mahmood S. Geographical variation in the epidemiology of esophageal cancer in Pakistan. Asian Pacific Journal of Cancer Prevention. 2005 Apr-Jun; 6(2): 139-42en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/37712
dc.language.isoengen_US
dc.source.urihttps://www.apocp.orgen_US
dc.subject.meshAdenocarcinoma --epidemiologyen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshCarcinoma, Squamous Cell --epidemiologyen_US
dc.subject.meshChilden_US
dc.subject.meshEsophageal Neoplasms --epidemiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLogistic Modelsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPakistan --epidemiologyen_US
dc.subject.meshRisk Factorsen_US
dc.titleGeographical variation in the epidemiology of esophageal cancer in Pakistan.en_US
dc.typeJournal Articleen_US
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