Serum Inflammatory Markers Of Diabetic Kidney Disease And Their Correlation To Lipid Parameters Among Diabetic Individuals Of Eastern India

Simple item page
dc.contributor.authorAcharjya, Donaen_US
dc.contributor.authorBanerjee, Ushasien_US
dc.contributor.authorBhattacharyya, Swatien_US
dc.date.accessioned2019-11-25T05:27:09Z
dc.date.available2019-11-25T05:27:09Z
dc.date.issued2019-01
dc.description.abstractBackground : Diabetes mellitus is the leading cause of chronic renal failure . As the period of diabetes progresses there is simultaneous increase of inflammatory markers like high sensitive C reactive protein (hsCRP) with degree of renal involvement, suggested by albumin creatinine ratio and also dyslipidemia in diabetic patients. Materials & Methods: 120 diabetic individuals aged (30-60) yrs, divided in 3 groups of 40 subjects in each, namely: a) newly diagnosed˂5 years b) 5-10 years after diagnosis and c) ≥10 years after diagnosis were recruited as study subjects from a tertiary care hospital in sub Himalayan region. Results : Descriptive studies showing mean values of hsCRP ,ACR & lipid parameters were done in all 3 groups. One-way ANOVAwith post hoc analysis after Bonferroni correction in 3 different groups enunciated a significant and statistical increase (p <.001) of both hsCRP &ACR with duration of diabetes unlike the lipid parameters. hsCRP, ACR, cholesterol & LDLeven illustrated a very significant correlation between each other (p<0.001) , TG to hsCRPwhile HDLshowed no correlation to any parameters. Conclusion: Early detection, monitoring of inflammatory markers hsCRP, ACR & deranged lipid parameters are predictors of diabetic nephropathy that can help in modulating diabetes and its complications.en_US
dc.identifier.affiliationsSenior Resident, Department of Biochemistry, North Bengal Medical College, Siliguri, Indiaen_US
dc.identifier.affiliationsAssistant Professor, Department of Biochemistry, North Bengal Medical College, Siliguri, India.*Corresponding Authoren_US
dc.identifier.affiliationsProfessor, Department of Biochemistry, Calcutta National Medical College, Kolkata, Indiaen_US
dc.identifier.citationAcharjya Dona , Banerjee Ushasi , Bhattacharyya Swati .An Epidemiological Study Of 104 Cases Of Papulosquamous Disorders In South India.International Journal of Scientific Research.2019 Jan;8(1):39-41en_US
dc.identifier.issn2277-8179
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/185350
dc.languageenen_US
dc.publisherWorld Wide Journalsen_US
dc.relation.issuenumber1en_US
dc.relation.volume8en_US
dc.subjectDiabetesen_US
dc.subjecthsCRPen_US
dc.subjectACRen_US
dc.subjectlipid parametersen_US
dc.titleSerum Inflammatory Markers Of Diabetic Kidney Disease And Their Correlation To Lipid Parameters Among Diabetic Individuals Of Eastern Indiaen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijsr2019v8n1p36.pdf
Size:
518.58 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal Of Scientific Research