Hypersensitivity reaction with metformin: a case report

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dc.contributor.authorVashisht, Tusharen_US
dc.contributor.authorNaidu, C. Dinesh M.en_US
dc.contributor.authorMandal, Chhandaen_US
dc.date.accessioned2020-04-23T07:59:29Z
dc.date.available2020-04-23T07:59:29Z
dc.date.issued2019-12
dc.description.abstractMetformin is a biguanide derivative widely used for treatment of diabetic patients. The most common toxic effects of metformin are gastrointestinal (anorexia, nausea, vomiting, abdominal discomfort and diarrhoea). As with other drugs, allergic reactions can occur with metformin also, but these are very rare. A case of hypersensitivity reaction with metformin was reported in adverse drug monitoring centre. A 59-year-old female, newly diagnosed case of diabetes mellitus II, started on metformin tablet 500 mg twice daily, developed purpuric skin lesions on her arms, legs and back few days after starting the drug. metformin was stopped and patient was put on glimepiride tablet. The lesions slowly started subsiding after stopping metformin.en_US
dc.identifier.affiliationsDepartment of Pharmacology, ANIIMS, Port Blair, Andaman and Nicobar, Indiaen_US
dc.identifier.affiliationsDepartment of Dermatology, ANIIMS, Port Blair, Andaman and Nicobar, Indiaen_US
dc.identifier.citationVashisht Tushar, Naidu C. Dinesh M., Mandal Chhanda. Hypersensitivity reaction with metformin: a case report. International Journal of Basic & Clinical Pharmacology. 2019 Dec; 8(12): 2763-2765en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/200466
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber12en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2319-2003.ijbcp20195293en_US
dc.subjectHypersensitivity reactionen_US
dc.subjectMetforminen_US
dc.subjectSkin lesionsen_US
dc.titleHypersensitivity reaction with metformin: a case reporten_US
dc.typeJournal Articleen_US
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