The study of the effect of C-PAP therapy in type-II diabetic patients with obesity and obstructive sleep apnea

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dc.contributor.authorSarkar, Poornima Deyen_US
dc.contributor.authorKumar, Arunen_US
dc.contributor.authorGopal, Krishnaen_US
dc.contributor.authorKachhawa, Poonamen_US
dc.contributor.authorSingh, Seemaen_US
dc.date.accessioned2020-09-24T07:34:31Z
dc.date.available2020-09-24T07:34:31Z
dc.date.issued2019-10
dc.description.abstractType II diabetes mellitus (T2DM) is closely associated with Obstructive sleep apnea (OSA) and obesity. Type 2 diabetes and OSA may be pathophysiologically independent conditions although the joint association with obesity or visceral adiposity. There is a consistent relationship between obesity and OSA, which has been reported in 60-90% of OSA patients. The prevalence of obesity increases with a parallel increase in the prevalence of OSA. Continuous positive airway pressure (CPAP) therapy is an effective choice of treatment for OSA, an overnight test, or titration some patients may reduce apnea events by minimizes airway collapse by CPAP. Several studies showed that the effect of drug treatment with 3 months of C-PAP in patients with type 2 diabetes. In the present study, we include 300 patients in different groups, out of the 100 patients undergoing treatment of CPAP therapy minimum for three months. Blood sugar, HbA1c, and lipid profile were measured and an overnight sleep study was done. The obtained data shows the significant effect of therapy on physiological and biochemical parameters. AHI and BMI were highly significant in group II and Group III when compared to group I. FBS, HbA1C, and Lipid profile parameters also gave significance results (p-value <0.001) in group II and group III when compared with healthy subjects (group I).en_US
dc.identifier.affiliationsDepartment of Biochemistry, Mahatma Gandhi Memorial Medical College, Indore, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Saraswathi Institute of Medical Sciences, Hapur, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Lala Lajpat Rai Memorial Medical College, Meerut Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Autonomous State Medical College, Shahjahanpur, Indiaen_US
dc.identifier.affiliationsDepartment of Biochemistry, Mahatma Gandhi Memorial Medical College, Indore, Indiaen_US
dc.identifier.citationSarkar Poornima Dey, Kumar Arun, Gopal Krishna, Kachhawa Poonam, Singh Seema. The study of the effect of C-PAP therapy in type-II diabetic patients with obesity and obstructive sleep apnea. International Journal of Research and Development in Pharmacy & Life Sciences (IJRDPL). 2019 Oct; 8(4): 18-21en_US
dc.identifier.issn2282-0238
dc.identifier.issn2393-932X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203824
dc.languageenen_US
dc.publisherSociety for research and Development in Educationen_US
dc.relation.issuenumber4en_US
dc.relation.volume8en_US
dc.source.urihttps://doi.org/10.21276/IJRDPL.2278-0238.2019.8(4).18-21en_US
dc.subjectSleep Apneaen_US
dc.subjectApnea Hypo-apnea Index (AHI)en_US
dc.subjectType II diabetes mellitusen_US
dc.subjectContinuous positive air pressure therapy (C-PAP)en_US
dc.subjectObesityen_US
dc.titleThe study of the effect of C-PAP therapy in type-II diabetic patients with obesity and obstructive sleep apneaen_US
dc.typeJournal Articleen_US
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