Effects of garlic (Allium sativum) extract on the heart rate, rhythm and force of contraction in frog: a dose-dependent study.

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dc.contributor.authorYadav, Raj Kumaren_US
dc.contributor.authorVerma, Nar Singhen_US
dc.date.accessioned2009-05-28T15:53:17Z
dc.date.available2009-05-28T15:53:17Z
dc.date.issued2004-06-21en_US
dc.description.abstractGarlic juice (dose equivalent to 3.3 g to 33 g garlic) mainly caused bradycardia in frog Rana tigerina. The disturbance in ventricular rhythm was observed prior to than that of atria. Rhythm was specially disturbed at higher doses causing bizarre pattern. Force of contraction of the heart also decreased with higher dose of the garlic extract. The results suggest that garlic extract has some beneficial effect on heart rate modulating the rate, rhythm and force of contraction positively but very high doses may exert non-desirable effects as well.en_US
dc.description.affiliationDepartment of Physiology, King George's Medical College, Lucknow 226 003, India. rajkumaryad@hotmail.comen_US
dc.identifier.citationYadav RK, Verma NS. Effects of garlic (Allium sativum) extract on the heart rate, rhythm and force of contraction in frog: a dose-dependent study. Indian Journal of Experimental Biology. 2004 Jun; 42(6): 628-31en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/62541
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAnimalsen_US
dc.subject.meshDose-Response Relationship, Drugen_US
dc.subject.meshElectrocardiographyen_US
dc.subject.meshFree Radicalsen_US
dc.subject.meshGarlic --metabolismen_US
dc.subject.meshHeart --drug effectsen_US
dc.subject.meshHeart Rate --drug effectsen_US
dc.subject.meshModels, Chemicalen_US
dc.subject.meshMuscle Contractionen_US
dc.subject.meshMyocardial Contraction --drug effectsen_US
dc.subject.meshPlant Extractsen_US
dc.subject.meshRanidaeen_US
dc.titleEffects of garlic (Allium sativum) extract on the heart rate, rhythm and force of contraction in frog: a dose-dependent study.en_US
dc.typeJournal Articleen_US
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