Naegleria Fowleri "The Brain -Eating Amoeba": A Review
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Date
2024-04
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Society for Healthcare & Research Development
Abstract
Naegleria fowleri is a free - living amoeba (FLA) that is commonly known as the “brain - eating amoeba.” This parasite can invade the central nervous system (CNS), causing an acute and fulminating infection known as primary amoebic meningoencephalitis (PAM). Even though PAM is characterized by low morbidity, it has shown a mortality rate of 98%, usually causing death in less than t wo weeks after the initial exposure. This review summarizes the most recent information about N. fowleri, its pathogenic molecular mechanism s, and the neuropathological processes implicated. Additionally, this review includes the main therapeutic strategies including the poss ible use of immunomodulatory agents to decrease neurological damage .
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Keywords
Brain eating amoeba, CNS, Neuroinflammation and Neurodegeneration
Citation
Mahajan A.. Naegleria Fowleri "The Brain -Eating Amoeba": A Review . Asian Journal of Medical Research. 2024 Apr; 13(2): 4-6