Evaluation of three different remineralizing agents on artificially demineralized enamel lesions Using scanning electron microscopy-energy dispersive X-ray and magic-angle spinning nuclear magnetic resonance - An in vitro study

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dc.contributor.authorMehta, Divya Vijayen_US
dc.contributor.authorSiddaiah, Shakuntala Ben_US
dc.date.accessioned2023-06-17T08:42:23Z
dc.date.available2023-06-17T08:42:23Z
dc.date.issued2022-07
dc.description.abstractAim: Demineralization can be arrested or reversed when remineralization agents are applied to incipient carious or noncavitated carious lesions. A large number of therapeutic agents, including nonfluoridated products, have been developed to promote enamel remineralization. This study aims to evaluate the efficacy of different remineralizing agents on artificially demineralized enamel lesions. Materials and Methods: The present in vitro study was conducted on 75 sound premolars divided into three groups of normal, demineralized (n = 15 each), and remineralized teeth (n = 45). The remineralized teeth were further subdivided into three groups (n = 15) as remineralized with 2% sodium fluoride (NaF), 2% NaF, and Psoralea corylifolia (bakuchi) and white mineral trioxide aggregate. Specimens of each group were treated with the above-mentioned remineralizing agents and then subjected to Vickers hardness number (VHN), scanning electron microscopy–energy dispersive X-ray (SEM-EDX), and magic-angle spinning nuclear magnetic resonance (MAS-NMR) for further evaluation. Results: The test results showed significantly the highest VHN and the emission peak of elements under the EDX test, such as calcium, phosphorous, oxygen, and fluorine with remineralized with NaF + bakuchi. MAS-NMR spectra showed fluorine and phosphorous peak in a group with NaF + bakuchi indicative of the increase in remineralization. NaF + bakuchi showed effective results in VHN, SEM-EDX, and MAS-NMR with no antagonist interaction. Conclusion: Thus, P. Corylifolia presents an advantage in enhancing remineralization and inhibiting demineralization for early carious lesions and can be used as a herbal extract for effective reduction in pathogenic bacteria.en_US
dc.identifier.affiliationsDepartment of Pediatric and Preventive Dentistry, Rajarajeswari Dental College and Hospital, Rajiv Gandhi University, Bengaluru, Karnataka, Indiaen_US
dc.identifier.citationMehta Divya Vijay, Siddaiah Shakuntala B. Evaluation of three different remineralizing agents on artificially demineralized enamel lesions Using scanning electron microscopy-energy dispersive X-ray and magic-angle spinning nuclear magnetic resonance - An in vitro study. Journal of indian society of pedodontics and preventive dentistry. 2022 Jul; 40(3): 330-337en_US
dc.identifier.issn0970-4388
dc.identifier.issn1998-3905
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/216841
dc.languageenen_US
dc.publisherWolters Kluwer – Medknowen_US
dc.relation.issuenumber3en_US
dc.relation.volume40en_US
dc.source.urihttps://doi.org/10.4103/jisppd.jisppd_282_22en_US
dc.subjectMagic-angle spinning nuclear magnetic resonanceen_US
dc.subjectPsoralea corylifolia (bakuchi)en_US
dc.subjectremineralizationen_US
dc.subjectscanning electron microscopy–energy dispersive X-rayen_US
dc.subjectsodium fluorideen_US
dc.subjectVickers hardness numberen_US
dc.titleEvaluation of three different remineralizing agents on artificially demineralized enamel lesions Using scanning electron microscopy-energy dispersive X-ray and magic-angle spinning nuclear magnetic resonance - An in vitro studyen_US
dc.typeJournal Articleen_US
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