Role Of Rapid Molecular Test To Detect Chlamydia Trachomatis And Neisseria Gonorrhoea In Diagnosing Subclinical Pid
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Date
2025-07
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Society for Health and Advanced Research
Abstract
Background: Pelvic Inflammatory Disease (PID), especially its subclinical form, remains a significant cause of infertility and reproductive morbidity in women. Chlamydia trachomatis and Neisseria gonorrhoeae are key pathogens implicated in PID, often remaining undetected due to asymptomatic infections. To evaluate the role of rapid molecular testing for Chlamydia trachomatis and Neisseria gonorrhoeae inObjectives: diagnosing subclinical PID among women attending a gynecology outpatient clinic. A cross-sectional study was conducted on 80Methods: women aged 18–45 years, divided into clinically diagnosed PID cases and controls. Endocervical swabs were analyzed using real-time PCR for Chlamydia trachomatis and Neisseria gonorrhoeae. Bacterial vaginosis was assessed via Nugent scoring and Amsel's criteria. PCRResults: positivity for Chlamydia trachomatis and Neisseria gonorrhoeae was significantly higher among clinical PID cases (p<0.05). Combined testing improved diagnostic sensitivity and specificity. Rapid molecular tests are effective in early detection of subclinical PID, enhancingConclusion: reproductive health outcomes.
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Keywords
Pelvic Inflammatory Disease, Chlamydia trachomatis, Neisseria gonorrhoeae, Polymerase Chain Reaction, Subclinical PID.
Citation
Girotra Parul, Gupta Smriti, Gupta Rekha, Singh Ravi Pratap, Khare Anjali. Role Of Rapid Molecular Test To Detect Chlamydia Trachomatis And Neisseria Gonorrhoea In Diagnosing Subclinical Pid. International Journal of Scientific Research. 2025 Jul; 14(7): 30-32