Role of Calcium Toxicity in Neurodegenerative Diseases

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dc.contributor.authorChughtai, Anjum Mirzaen_US
dc.contributor.authorAhmed, Nisar Gen_US
dc.contributor.authorAgrawal, D Ken_US
dc.contributor.authorSinghal, Sangeetaen_US
dc.date.accessioned2019-11-16T07:25:08Z
dc.date.available2019-11-16T07:25:08Z
dc.date.issued2019-01
dc.description.abstractBackground: Neurodegenerative diseases are those affect the central nervous system (brain, spinal cord) and peripheral nervous system. It is characterized by progressive loss of neurons and synapses in these nervous systems. Calcium homeostasis receives key attention in the past few years in the field of neuronal physiology of Ageing and Neurodegenerative diseases. Objective: The aim of this study was to evaluate Calcium homeostasis in patients with Neurodegenerative diseases. Methods: 50 subjects (36 males and 14females) with Neurodegenerative diseases. And same number of healthy age-matched subject control group was assessed. A complete & detailed neurological examination were performed in all individuals and clinically evaluated for the occurrence of Neurodegenerative diseases. Calcium levels were estimated using (Instrumentation Laboratory – IlyteTM) Automated Electrolyte Analyzer, with solution pack and reagents. Results: ‘The Serum Calcium (Ca2+) levels were estimated and comparison was done in both control and case group separately, for evaluating the changes due to ageing and in particular to neurodegenerative diseases. Conclusion: Neurodegenerative diseases showed significant differences in Calcium homeostasis.en_US
dc.identifier.affiliationsAssociate Professor; Department of Medicine, J.N.M.C., A.M.U., Aligarh, India.en_US
dc.identifier.affiliationsResearch Scholar; Department of Physiology, J.N.M.C., A.M.U., Aligarh, Indiaen_US
dc.identifier.affiliationsProfessor; Department of Physiology, J.N.M.C., A.M.U., Aligarh, Indiaen_US
dc.identifier.affiliationsProfessor; Department of Physiology, J.N.M.C., A.M.U., Aligarh, Indiaen_US
dc.identifier.citationChughtai Anjum Mirza, Ahmed Nisar G, Agrawal D K, Singhal Sangeeta. Role of Calcium Toxicity in Neurodegenerative Diseases. International Archives of BioMedical and Clinical Research. 2019 Jan-Mar; 5(1): 20-25en_US
dc.identifier.issn2454-9894
dc.identifier.issn2454-9886
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/184302
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber1en_US
dc.relation.volume5en_US
dc.source.urihttps://doi.org/10.21276/iabcr.2019.5.1.07en_US
dc.subjectNeurodegenerative diseasesen_US
dc.subjectCalcium Homeostasis.en_US
dc.titleRole of Calcium Toxicity in Neurodegenerative Diseasesen_US
dc.typeJournal Articleen_US
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