A Comparative Evaluation of Rapid Card Test with Enzyme- Linked Immunosorbent Assay for the Detection of HBsAg Among Pregnant Women in a Tertiary Care Hospital

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dc.contributor.authorSharma, Meghaen_US
dc.contributor.authorGolia, Sarojen_US
dc.contributor.authorMehra, S Ken_US
dc.contributor.authorJani, Manoj Ven_US
dc.date.accessioned2019-11-16T07:25:08Z
dc.date.available2019-11-16T07:25:08Z
dc.date.issued2019-01
dc.description.abstractBackground: Hepatitis B virus infection is an important health problem and a leading cause of death worldwide. The most important marker for HBV infection is HBsAg. A proper identification of kit is required for proper diagnosis of infection, as well as disease management and prevention. Aims& Objective: - The aim of the present study was to compare rapid HBsAg detection ICT kits for the screening of HBV infection with gold standard ELISA method. Methods: The study comprised 500 blood samples of pregnant women. These samples were tested with ICT kits of (Hepa Card Company) and ELISA (HEPLISA by J. Mitra.). Results: In present study we found 100% sensitivity, 99.59% specificity, 81.81% positive predictive value ,100%Negative predictive value and 99.60% diagnostic efficiency of rapid card test with comparison to ELISA for HBsAg detection. Conclusion: The present study concluded that the overall performance of the rapid ICT kit for HBsAg was equally sensitive to ELISA and yet they were cheap and quicker. It can be recommended that ELISA comparable rapid devices may be allowed to be used for preliminary screening of HBsAg especially in remote areas or where cost is an issue.en_US
dc.identifier.affiliationsAssistant Professor, Dept. of Microbiology, Ananta Institute of Medical Sciences Research Centre, Rajsamanden_US
dc.identifier.affiliationsProfessor, Dept. of Microbiology, Ananta Institute of Medical Sciences Research Centre, Rajsamanden_US
dc.identifier.affiliationsEx- Professor & Head, Department of Microbiology, Geetanjali Medical College & Hospital, Udaipuren_US
dc.identifier.affiliationsAssistant Professor, Department of TB & Chest, Ananta Institute of Medical Sciences Research Centre, Rajsamanden_US
dc.identifier.citationSharma Megha, Golia Saroj, Mehra S K, Jani Manoj V. A Comparative Evaluation of Rapid Card Test with Enzyme- Linked Immunosorbent Assay for the Detection of HBsAg Among Pregnant Women in a Tertiary Care Hospital. International Archives of BioMedical and Clinical Research. 2019 Jan-Mar; 5(1): 31-33en_US
dc.identifier.issn2454-9894
dc.identifier.issn2454-9886
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/184292
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber1en_US
dc.relation.volume5en_US
dc.source.urihttps://doi.org/10.21276/iabcr.2019.5.1.09en_US
dc.subjectHBsAgen_US
dc.subjectImmunochromatographic kit ICTen_US
dc.subjectELISAen_US
dc.subjectcomparison for effectiveness.en_US
dc.titleA Comparative Evaluation of Rapid Card Test with Enzyme- Linked Immunosorbent Assay for the Detection of HBsAg Among Pregnant Women in a Tertiary Care Hospitalen_US
dc.typeJournal Articleen_US
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