Epidemiology of ocular malignancies in Karachi.

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dc.contributor.authorBhurgri, Yasminen_US
dc.contributor.authorBhurgri, Hadien_US
dc.contributor.authorUsman, Ahmeden_US
dc.contributor.authorFaridi, Naveenen_US
dc.contributor.authorMalik, Jawaiden_US
dc.contributor.authorPuri, Rehanen_US
dc.contributor.authorMirza, Meheken_US
dc.contributor.authorBhurgri, Asifen_US
dc.contributor.authorAhmed, Rashidaen_US
dc.contributor.authorMuzaffar, Suhailen_US
dc.contributor.authorKayani, Nailaen_US
dc.contributor.authorPervez, Shahiden_US
dc.contributor.authorHasan, Sheema Hen_US
dc.contributor.authorSoomro, Akber Haideren_US
dc.date.accessioned2009-05-27T17:29:35Z
dc.date.available2009-05-27T17:29:35Z
dc.date.issued2003-08-20en_US
dc.descriptionAsian Pacific Journal of Cancer Prevention.en_US
dc.description.abstractThe study was conducted with the objective of examining descriptive epidemiological characteristics of malignant ocular tumours in Karachi (1998-2002). The data for two hundred and forty two ocular malignancies registered at the Karachi Cancer Registry for Karachi Division during a 5-year period, from January 1(st) 1998 to December 31(st) 2002 were analysed. The age standardized incidence rate (ASIR) was 0.5/100,000 in males and 0.4/100,000 in females. The gender ratio (M:F) was 1.3. The mean age was 34.8 years (95% CI 30.1; 39.6) in males and 34.5 years (95% CI 28.0; 40.9) in females. A fourth of the malignancies were childhood tumours. The most common childhood malignancies were retinoblastomas and rhabdomyosarcomas, whereas the most common adult malignancies were conjunctival squamous cell carcinomas and melanomas. Approximately 97.0% of the tumours were histologically confirmed. The majority (62.5%) presented as low-grade (grade 1) lesions, and were localized to the eye (50%) at the time of diagnosis. The annual incidence rates remained stable during this period. The crucial importance of ocular malignancies is the high 5-year survival rates, associated disability following unilateral or bilateral enucleation and the implications as preventable components of Cancer Control Programs This article provides demographic statistics, which could be useful for the foundation, establishment and monitoring of a component of an effective cancer control program, the risk factors of ocular malignancies being well established. It is recommended that public health education to prevent ultraviolet light related ocular malignancies, information on preventative sun protection behavior, legislation for occupation related ocular cancers and genetic counseling for familial retinoblastoma should be essential primary components of all National Cancer Control Programs even in apparently low risk countries. In the long-term perspective, these efforts should further reduce the incidence - meanwhile stabilization of incidence rates could be achieved. Early detection and standardized treatment will reduce the associated morbidity and mortality.en_US
dc.description.affiliationKarachi Cancer Registry, Department of Pathology, Stadium Road, P.O. Box 3500, Karachi 74800, Pakistan. bhurgri@cyber.net.pken_US
dc.identifier.citationBhurgri Y, Bhurgri H, Usman A, Faridi N, Malik J, Puri R, Mirza M, Bhurgri A, Ahmed R, Muzaffar S, Kayani N, Pervez S, Hasan SH, Soomro AH. Epidemiology of ocular malignancies in Karachi. Asian Pacific Journal of Cancer Prevention. 2003 Aug-Dec; 4(4): 352-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/37263
dc.language.isoengen_US
dc.source.urihttps://www.apocp.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshEye Neoplasms --epidemiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPakistan --epidemiologyen_US
dc.titleEpidemiology of ocular malignancies in Karachi.en_US
dc.typeJournal Articleen_US
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