Relationship of chronic periodontitis and plasma C - reactive protein during pregnancy.

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dc.contributor.authorNavkiran
dc.contributor.authorKaur, A
dc.contributor.authorSingh, Shuchita
dc.contributor.authorVerma, A
dc.date.accessioned2016-11-05T07:27:07Z
dc.date.available2016-11-05T07:27:07Z
dc.date.issued2016-07
dc.description.abstractBackground: Maternal periodontal disease is a chronic oral infection with local and systemic inflammatory responses and may be associated with adverse pregnancy outcomes. Elevated levels of Creactive protein has been linked to adverse pregnancy outcomes in maternal periodontal disease. Objectives: To assess plasma C-reactive protein levels in pregnant women with chronic periodontitis and in periodontal health and to compare the incidence of preterm delivery in pregnant women having chronic periodontitis and in periodontal health. Materials and Methods: A total of 122 pregnant women aged 18 years and above with gestational age < 26 weeks were recruited and divided into two equal groups (control group, study group) of 61 each. Blood samples were taken from both the groups to determine the serum C-reactive protein. Results: The mean value of C-reactive protein levels in subjects having chronic periodontitis was higher compared to control group i.e., 2.462±0.318 compared to 1.307±0.361 (P<0.001). The incidence of preterm delivery (< 37 weeks) was 82% in the chronic periodontitis group (study group) compared to 3.3% in the control group (P< 0.001). The incidence of low birth weight(<2500g) was 45.9% in chronic periodontitis (study group) compared to 14.8% in the control group (p< 0.001). Conclusion: The findings from the study suggest that periodontal disease in pregnant women is associated with increased C-reactive protein levels in pregnancy. Incidence of preterm delivery and low birth weight infants is higher in pregnant women with chronic periodontitis compared to healthy controls.en_US
dc.identifier.citationNavkiran, Kaur A, Singh S, Verma A. Relationship of chronic periodontitis and plasma C - reactive protein during pregnancy. International Journal of Medical and Dental Sciences. 2016 July; 5(2): 1208-1213.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/178241
dc.language.isoenen_US
dc.source.urihttps://ijmds.org/wp-content/uploads/2016/06/1208-1213-RA-Chr-peri.pdfen_US
dc.subjectC-reactive proteinen_US
dc.subjectpreterm birthen_US
dc.subjectlow birth weighten_US
dc.titleRelationship of chronic periodontitis and plasma C - reactive protein during pregnancy.en_US
dc.typeArticleen_US
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