Antidepressant-Induced Sexual Dysfunction: A comparison between Duloxetine and Escitalopram.

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dc.contributor.authorJhanjee, Anurag
dc.contributor.authorKumar, Pankaj
dc.contributor.authorGupta, Neeraj Kumar
dc.date.accessioned2015-07-06T06:20:43Z
dc.date.available2015-07-06T06:20:43Z
dc.date.issued2010-04
dc.description.abstractBackground: Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) have the potential to produce delayed ejaculation in men, delayed orgasm or anorgasmia in women and decreased libido that is independent of the gender. The occurrence of medication-associated sexual dysfunction increases the likelihood of medication non-compliance (or non-adherence) in patients, which may contribute to untreated depression and/or disease relapse. Materials & Methods: 60 patients with diagnosis of Depressive episode (in remission at the time of study), divided into 2 groups of 30 patients taking Duloxetine and the remaining 30 patients taking Escitalopram, were recruited on consecutive basis from the patients attending Psychiatry OPD of Lady Hardinge Medical College (LHMC). Each subject was rated on Arizona Sexual Experience Scale (ASEX) and the results obtained were statistically analyzed. Results: In the present study the average ASEX score obtained in the Escitalopram group (12.63) was found to be more than that in Duloxetine group (12.36), though this difference was not found to be statistically significant. Conclusions: These results illustrate that antidepressant-induced sexual dysfunction is reported frequently by patients taking SSRIs or SNRIs. Our study did not find any significant difference between escitalopram and duloxetine with respect to their sexual dysfunction profile but in view of the limitations of our study there is need for further research in this domain of psychopharmacology.en_US
dc.identifier.citationJhanjee Anurag, Kumar Pankaj, Gupta Neeraj Kumar. Antidepressant-Induced Sexual Dysfunction: Acomparison between Duloxetine and Escitalopram. Delhi Psychiatry journal. 2010 Apr; 13 (1): 89-93.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/159105
dc.language.isoenen_US
dc.source.urihttps://medind.nic.in/daa/t10/i1/daat10i1p89.pdfen_US
dc.subjectEscitalopramen_US
dc.subjectduloxetineen_US
dc.subjectArizona Sexual Experience Scale (ASEX)en_US
dc.subject.meshAntidepressive Agents --adverse effects
dc.subject.meshCitalopram --adverse effects
dc.subject.meshDuloxetine Hydrochloride --adverse effects
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshIndia
dc.subject.meshMale
dc.subject.meshPsychometrics
dc.subject.meshSexual Behavior
dc.subject.meshSexual Dysfunction, Physiological --chemically induced
dc.subject.meshSexual Dysfunction, Physiological --etiology
dc.subject.meshSexual Dysfunction, Physiological --statistics & numerical data
dc.subject.meshSexual Dysfunctions, Psychological --chemically induced
dc.subject.meshSexual Dysfunctions, Psychological --etiology
dc.subject.meshSexual Dysfunctions, Psychological --statistics & numerical data
dc.titleAntidepressant-Induced Sexual Dysfunction: A comparison between Duloxetine and Escitalopram.en_US
dc.typeArticleen_US
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