Antibiotic Sensitivity Pattern of Burkholderia cepacia complex in blood stream infections in a tertiary care hospital

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dc.contributor.authorPatel, Dhwanien_US
dc.contributor.authorMavani, Monikaen_US
dc.contributor.authorParmar, Kajalen_US
dc.contributor.authorJavadekar, Tanujaen_US
dc.contributor.authorLakhani, Suchetaen_US
dc.date.accessioned2025-05-09T06:20:36Z
dc.date.available2025-05-09T06:20:36Z
dc.date.issued2024-02
dc.description.abstractIntroduction: Burkholderia cepacia complex (BCC) is ubiquitous in nature, present in water, soil, and plants. BCC is comprised of Gram-negative non-lactose-fermenting bacteria. Gram negative, non lactose fermenting Burkholderia cepacia complex has emerged as an opportunistic nosocomial pathogen causing significant morbidity and mortality in hospitalized patients owing to its high antibiotic resistance. This study was aimed to determine prevalence of Burkholderia cepacia complex and to evaluate sensitivity pattern of Burkholderia cepacia complex in blood stream infections in Dhiraj Hospital, Gujarat which is a tertiary care hospital and teaching institute. Materials and Methods: The present study was conducted in the Department of Microbiology for a period from January 2022 to December 2022 of Dhiraj General Hospital, SBKS MI & RC, Waghodia, Gujarat. All samples were received in central laboratory and blood cultures were processed in BD BACTEC FX40. The positive culture bottles were sub cultured on Mac Conkey agar, Blood agar and Nutrient agar and were incubated for 24 hours at 37?C.The data was collected and analyzed statistically. Results: During the study period 31 positive samples for BCC were isolated from a total of 612 culture samples, thus the prevalence rate was 5.06% in our setup. BCC was found majorly in ICUs (65%) and in wards (35%).The isolates showed maximum sensitivity to Co-Trimoxazole (83.87%), followed by Ceftazidime (58.06%), Meropenem (54.83%) and Minocycline (51.61%).Conclusion: From various studies and our study we could conclude that there were variations in the results of drug sensitivity. So, there is need to properly isolate and do antibiotic sensitivity testing for better patient management. Prompt diagnosis is essential step to reduce mortality and establish infection control practices.en_US
dc.identifier.affiliationsResident Doctor, Department of Microbiology, SBKS MI & RC, Sumandeep Vidyapeeth, Vadodara, Gujarat, Indiaen_US
dc.identifier.affiliationsResident Doctor, Department of Microbiology, SBKS MI & RC, Sumandeep Vidyapeeth, Vadodara, Gujarat, Indiaen_US
dc.identifier.affiliationsResident Doctor, Department of Microbiology, SBKS MI & RC, Sumandeep Vidyapeeth, Vadodara, Gujarat, Indiaen_US
dc.identifier.affiliationsProfessor and Head, Department of Microbiology, SBKS MI & RC, Sumandeep Vidyapeeth, Vadodara, Gujarat, Indiaen_US
dc.identifier.affiliationsProfessor, Department of Microbiology, SBKS MI & RC, Sumandeep Vidyapeeth, Vadodara, Gujarat, Indiaen_US
dc.identifier.citationPatel Dhwani, Mavani Monika, Parmar Kajal, Javadekar Tanuja, Lakhani Sucheta . Antibiotic Sensitivity Pattern of Burkholderia cepacia complex in blood stream infections in a tertiary care hospital. International Archives of Integrated Medicine. 2024 Feb; 11(2): 18-21en_US
dc.identifier.issn2394-0026
dc.identifier.issn2394-0034
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/242663
dc.languageenen_US
dc.publisherEducational Society for Excellenceen_US
dc.relation.issuenumber2en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.5281/zenodo.10693975en_US
dc.subjectBurkholderia cepacia complexen_US
dc.subjectDrug sensitivityen_US
dc.subjectOpportunistic nosocomial pathogenen_US
dc.titleAntibiotic Sensitivity Pattern of Burkholderia cepacia complex in blood stream infections in a tertiary care hospitalen_US
dc.typeJournal Articleen_US
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