Major Depressive Disorder: Part-II -Comorbid Anxiety Disorders.
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Date
2010-04
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Abstract
Objective: To demonstrate that Anxiety Disorder comorbidity is reflection of underlying
common risk factors (Anxiety proneness) in Major Depressive Disorder patients and may
not be a separate disorder. We hypothesized that “Anxious personality traits or disorders
under stress take the form of state that is Anxiety Disorders”. Methods:36 indoor patients
of psychiatry ward of tertiary level services, out of total 168 admitted patients from Ist
January 2008 to 31st Dec. 2008 diagnosed as Major Depressive Disorder (as per DSMIV
TR). Socio-demographic data on a self-designed Performa, Montgomery Asberg’s
Depression Rating Scale (MADRS), Hamilton Anxiety rating scale (HARS) and Presumptive
Stressful Life Event Scale (PSLE) were applied to these patients and they were observed
every alternate day till discharge. International Personality Disorder Examination (IPDE)
was applied on their third follow-up visit, which ranged from 6 to8 weeks. Results: High
level of co-existence of Anxiety disorder 29(80.5%) in the study sample, 11 patients (30.55%)
of Major Depressive Disorder had personality disorder level of psychopathology and
18(50%) patient of Major Depressive Disorder had double or more personality traits
psychopathology and there were 7(19.45%) patients of Major Depressive Disorder had
only single trait personality psychopathology. Conclusion: This work support the gene
environmental diathesis where vulnerable person under stress develop Axis I disorder
which are considered currently as co morbid disorders.
Description
Keywords
Major depressive disorder, phenomenology, personality, psychopathology, comorbidity
Citation
Gocher Suresh, Gupta L N, Singhal A K, Verma K K, Gupta Prerana, Prasad Shiv, Agrawal P P, Yadav S P, Gupta Prachi. Major Depressive Disorder: Part-II -Comorbid Anxiety Disorders. Delhi Psychiatry journal. 2010 Apr; 13 (1): 61-69.