Association Between Neonatal Thyroid Stimulating Hormone Status and Maternal Urinary Iodine Status

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dc.contributor.authorSait, Haseenaen_US
dc.contributor.authorKapoor, Seemaen_US
dc.contributor.authorJindal, Ankuren_US
dc.contributor.authorGarg, Ritikaen_US
dc.contributor.authorBelwal, Ravi Shankaren_US
dc.contributor.authorYadav, Sangitaen_US
dc.contributor.authorGupta, Sangeetaen_US
dc.contributor.authorThelma, BKen_US
dc.date.accessioned2020-04-23T07:43:49Z
dc.date.available2020-04-23T07:43:49Z
dc.date.issued2019-06
dc.description.abstractBackground: Maternal urinary iodine concentration (MUIC) andpercentage of neonates with Thyroid stimulating hormone (TSH)>5 mIU/L are amongst the parameters suggested for assessingadequate iodine status.Objective: To assess the correlation between MUIC andneonatal TSH levels.Study design: Cross-sectional.Settings: Tertiary care center in Delhi, India, between November2015 to November 2016.Participants: Postnatal mother-neonate dyads.Methods: TSH levels assessed among neonatal samples werestratified as below and above 5 mIU/L. MUIC was measured in544 mothers, 400 mother-neonate dyads with neonatal TSHlevels >5 mIU/L (cases) and 144 mother-neonate newbornmother dyads with neonatal TSH <5 mIU/L (controls).Results: The percentage of mothers with iodine insufficiency(9.8% vs 5.6%) as well as iodine excess (54.3% vs 41.7%) weresignificant higher in cases than controls. Mean TSH was alsohigher (P=0.0002) in both the iodine deficient and iodine excessgroup. There was no correlation between neonatal TSH valuesand MUIC.Conclusions: Lack of correlation between neonatal TSH andMUIC is due to iodine excess together with iodine deficiency.en_US
dc.identifier.affiliationsDepartments of Pediarics, Lok Nayak Hospital and Maulana Azad Medical Collegeen_US
dc.identifier.affiliationsDepartments of Pediarics, Lok Nayak Hospital and Maulana Azad Medical Collegeen_US
dc.identifier.affiliationsObstretics and Gynecology, Lok Nayak Hospital and Maulana Azad Medical Collegeen_US
dc.identifier.affiliationsHuman Nutrition Unit, AIIMSen_US
dc.identifier.affiliationsDepartment of Genetics, University of Delhi – South Campus; New Delhi, Indiaen_US
dc.identifier.citationSait Haseena, Kapoor Seema, Jindal Ankur, Garg Ritika, Belwal Ravi Shankar, Yadav Sangita, Gupta Sangeeta, Thelma BK. Association Between Neonatal Thyroid Stimulating Hormone Status and Maternal Urinary Iodine Status. Indian Pediatrics. 2019 Jun; 56(6): 472-475en_US
dc.identifier.issn0974-7559
dc.identifier.issn0019-6061
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/199225
dc.languageenen_US
dc.publisherIndian Academy of Pediatricsen_US
dc.relation.issuenumber6en_US
dc.relation.volume56en_US
dc.source.urihttps://www.indianpediatrics.net/june2019/472.pdfen_US
dc.subjectNewbornscreeningen_US
dc.subjectPostpartumen_US
dc.subjectPovidoneiodine,Pregnanten_US
dc.subjectTSH.en_US
dc.titleAssociation Between Neonatal Thyroid Stimulating Hormone Status and Maternal Urinary Iodine Statusen_US
dc.typeJournal Articleen_US
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