An epidemiological survey to assess the clinical use of cephalosporins in community-acquired respiratory tract infections.

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dc.contributor.authorSobti, Vikram
dc.contributor.authorKrishnaprasad, K
dc.contributor.authorBhargava, Amit
dc.date.accessioned2015-11-05T10:14:40Z
dc.date.available2015-11-05T10:14:40Z
dc.date.issued2015-05
dc.description.abstractBackground: In outpatient management of respiratory tract infections, the clinicians’ preferences always have a broad spectrum of antibiotics as an empirical therapy. Clinical use of cephalosporins and fluoroquinolones has been recommended by various international guidelines as a monotherapy or as combination therapy to manage these. This survey was conducted to assess the in-clinic use and preference of cephalosporins or fluoroquinolones as monotherapy or as combination therapy in managing respiratory tract infections by Indian doctors. Methods: A survey questionnaire was drafted to capture the feedback from crossspecialty regarding the preference of using antibiotics in respiratory tract infection in real time clinical settings. Results: Data from 163 physicians were collected and evaluated across India. 79 (48%) clinicians reported pharyngitis/tonsillitis to be the most commonly encountered respiratory tract infection followed by community-acquired pneumonia (CAP) 62 (38%). 100 (61%) clinicians preferred use of cefpodoxime monotherapy as a primary line of treatment for the management of respiratory pharyngitis/ tonsillitis. Use of short course therapy (≤1 week) of cefpodoxime and levofloxacin as combination therapy is preferred by 94 (58%) clinicians, in cases of acute exacerbation of chronic bronchitis (AECB) 85 (52%), and CAP 83 (51%). The clinical preference of levofloxacin was observed with only 16 (10%) clinicians, in lower respiratory tract infections, i.e. AECB and CAP. Conclusion: In-clinic use of cefpodoxime as monotherapy is preferred in upper respiratory tract infections. However, clinicians recommend a combination therapy of cefpodoxime and levofloxacin in lower respiratory tract infections.en_US
dc.identifier.citationSobti Vikram, Krishnaprasad K, Bhargava Amit. An epidemiological survey to assess the clinical use of cephalosporins in community-acquired respiratory tract infections. International Journal of Basic & Clinical Pharmacology. 2015 May-Jun; 4(3): 547-550.en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/165124
dc.language.isoenen_US
dc.source.urihttps://www.ijbcp.com/?mno=187034en_US
dc.subjectCephalosporinsen_US
dc.subjectFluoroquinolonesen_US
dc.subjectRespiratory tract infectionsen_US
dc.titleAn epidemiological survey to assess the clinical use of cephalosporins in community-acquired respiratory tract infections.en_US
dc.typeArticleen_US
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