The Anaesthetic Potency of Intrathecally Administered Levobupivacaine and Racemic Bupivacaine: A Hospital-Based Study

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dc.contributor.authorUpadhyay, Manoj Kumaren_US
dc.contributor.authorAgarwal, Anuragen_US
dc.contributor.authorDhama, Vipinen_US
dc.contributor.authorDas, P Ken_US
dc.contributor.authorMalviya, Deepaken_US
dc.date.accessioned2019-11-16T07:23:57Z
dc.date.available2019-11-16T07:23:57Z
dc.date.issued2018-04
dc.description.abstractBackground: Lower limb surgeries are often performed under spinal anesthesia. The conventional anesthetic method for lower limb surgeries is caudal epidural block. The currently available local anesthetic for this purpose is Bupivacaine which has long duration of action of around 6-12 hour. Methods: 60 adult cases ranging in age from 20 to 60 years with ASA Grade I and II requiring elective lower limb surgery under epidural anesthesia were selected for this prospective, randomized, double-blind study. Results: 60 adult cases ranging in age from 20 to 60 years with ASA Grade I and II, requiring elective gynecological surgery under epidural anesthesia were selected for this study. Cases were randomly allocated into two groups containing 20 cases each. Cases in Group B received Bupivacaine 0.25% and those in Group T received Tramadol 100mg. Conclusion: Current study concluded that both intrathecally administered levobupivacaine and racemic bupivacaine are safe and effective local anaesthetics for lower limb surgeries. Overall parameters observed in this study showed no significant difference between the two forms of the same drug. However, intrathecal levobupivacaine produces less toxicity.en_US
dc.identifier.affiliationsAssociate Professor, Dept. of Anaesthesiology, G. S. V. M. Medical College, Kanpur UP, Indiaen_US
dc.identifier.affiliationsAssociate Professor; Dept. of Emergency Medicine, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknowen_US
dc.identifier.affiliationsAssociate Professor; Dept. of Emergency Medicine, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknowen_US
dc.identifier.affiliationsAdditional Professor, Dept. of Emergency Medicine, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknowen_US
dc.identifier.affiliationsHoD, Dept. of Anaesthesiology; Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknowen_US
dc.identifier.citationUpadhyay Manoj Kumar, Agarwal Anurag, Dhama Vipin, Das P K, Malviya Deepak. The Anaesthetic Potency of Intrathecally Administered Levobupivacaine and Racemic Bupivacaine: A Hospital-Based Study. International Archives of BioMedical and Clinical Research. 2018 Apr-Jun; 4(2): 122-124en_US
dc.identifier.issn2454-9894
dc.identifier.issn2454-9886
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/184149
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber2en_US
dc.relation.volume4en_US
dc.source.urihttps://doi.org/10.21276/iabcr.2018.4.2.35en_US
dc.subjectAnaestheticen_US
dc.subjectLevobupivacaineen_US
dc.subjectBupivacaineen_US
dc.subjectIntrathecallyen_US
dc.titleThe Anaesthetic Potency of Intrathecally Administered Levobupivacaine and Racemic Bupivacaine: A Hospital-Based Studyen_US
dc.typeJournal Articleen_US
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