Changes in pancreatic beta cell function during growth and reproductive maturity of rats.

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dc.contributor.authorMukherjee, Ben_US
dc.contributor.authorChandrasekar, Ben_US
dc.contributor.authorMukherjee, S Ken_US
dc.date.accessioned2009-05-28T13:52:43Z
dc.date.available2009-05-28T13:52:43Z
dc.date.issued1989-06-01en_US
dc.description.abstractAn attempt has been made to study the changes, if any, in the efficiency of pancreatic beta cell function at different ages using one experimental model. For this, pancreatic islets were isolated from albino rats of 3, 8, 12 and 36 weeks of age and challenged with various concentrations of glucose (11.0, 16.7 and 22.2 mM). Significantly higher rate of glucose stimulated (pro)insulin biosynthesis was seen in the islets from 3 week old rats as compared to the islets obtained from 8, 12 and 36 week rats. On the other hand, immunoreactive insulin release was observed to be highest from islets of 8 week old rats followed by that of 12, 36 and 3 week old ones.en_US
dc.identifier.citationMukherjee B, Chandrasekar B, Mukherjee SK. Changes in pancreatic beta cell function during growth and reproductive maturity of rats. Indian Journal of Experimental Biology. 1989 Jun; 27(6): 502-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/59982
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAging --physiologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshGlucose --pharmacologyen_US
dc.subject.meshInsulin --secretionen_US
dc.subject.meshIslets of Langerhans --metabolismen_US
dc.subject.meshMaleen_US
dc.subject.meshProinsulin --biosynthesisen_US
dc.subject.meshRatsen_US
dc.subject.meshSexual Maturation --physiologyen_US
dc.titleChanges in pancreatic beta cell function during growth and reproductive maturity of rats.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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