Multiple Osteomas of Mandible in a Patient with Gardner’s Syndrome - Report of a Case
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Date
2023-06
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Publisher
Kairali Society of Oral and Maxillofacial Pathologists
Abstract
Introduction: Osteomas are benign tumors of the bone usually seen in craniofacial bones which arise from either the cortex or medulla. They are usually asymptomatic with slow painless growth. Multiple osteomas are often associated with Gardners syndrome. Solitary osteomas are typically non syndromic. Case Presentation: The patient presented with remarkable facial asymmetry following the growth in the mandible. Multiple os- teomas were noted which invoked suspicion of a syndrome. On endoscopic evaluation the patient was found to have multiple intestinal polyps, pathgnomonic for Gardners syndrome. Management and prognosis: The lesion was surgically removed under local anaesthesia. as an excisional biopsy and the asymmetry was rectified. Histopathologic examination revealed it to be ivory osteoma with dense compact bone and less mar- row spaces. The jaw lesions would precede the development of colonic polyps and therefore may contribute to early diagnosis of Gardner’s syndrome. There is also a chance of malignant evolution associated with the polyps Conclusion: People with the condition have a higher risk of developing other family adenomatous polyp (FAP)related cancers including pancreatic cancer and liver cancer. The patient should be in close follow up
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Keywords
Benign, Facial asymmetry, FAP, Gardners Syndrome, Intestinal polyps, Malignancy
Citation
George A, Vichattu SV, Das RJ, Thomas A, James JE.. Multiple Osteomas of Mandible in a Patient with Gardner’s Syndrome - Report of a Case. Oral and Maxillofacial Pathology Journal. 2023 Jun; 14(1): 131-133