Safety of oral graded challenges as a diagnostic approach hypersensitivity reaction to anti-tuberculosis drugs: a case report

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dc.contributor.authorDwipayana, Putu Adityaen_US
dc.contributor.authorSuryana, Ketuten_US
dc.date.accessioned2023-08-28T06:36:35Z
dc.date.available2023-08-28T06:36:35Z
dc.date.issued2022-12
dc.description.abstractTuberculosis (TB) still becomes a significant health problem in developing countries, especially in Indonesia. Allergy to antitubercular drugs is a real hindrance to the management of TB. The first-line anti-TB drug (ATD) is still the most effective TB drug, but it can have some side effects. One of these side effects is drug hypersensitivity reactions (DHR) which can affect a patient's compliance. The recommended diagnostic approach to DHR is a graded challenge by introducing drugs safely and optimally under a threshold dose until the usual daily dose is reached. We present a case of DHR to ATB drug and oral graded challenge as the diagnosis approach.en_US
dc.identifier.affiliationsDepartment of Internal Medicine, Wangaya General Hospital, Denpasar, Bali, Indonesiaen_US
dc.identifier.affiliationsDepartment of Internal Medicine, Merpati Clinic HIV, Allergy-Clinical Immunology Services Unit, Wangaya General Hospital, Denpasar, Bali, Indonesiaen_US
dc.identifier.citationDwipayana Putu Aditya, Suryana Ketut. Safety of oral graded challenges as a diagnostic approach hypersensitivity reaction to anti-tuberculosis drugs: a case report. International Journal of Advances in Medicine. 2022 Dec; 9(12): 1203-1206en_US
dc.identifier.issn2349-3933
dc.identifier.issn2349-3925
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/225931
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber12en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3933.ijam20223022en_US
dc.subjectGraded challengesen_US
dc.subjectSafetyen_US
dc.subjectDHRen_US
dc.titleSafety of oral graded challenges as a diagnostic approach hypersensitivity reaction to anti-tuberculosis drugs: a case reporten_US
dc.typeJournal Articleen_US
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