Dental caries vaccine.

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dc.contributor.authorShivakumar, K Men_US
dc.contributor.authorVidya, S Ken_US
dc.contributor.authorChandu, G Nen_US
dc.date.accessioned2009-05-28T07:47:51Z
dc.date.available2009-05-28T07:47:51Z
dc.date.issued2009-01-02en_US
dc.description.abstractDental caries is one of the most common diseases in humans. In modern times, it has reached epidemic proportions. Dental caries is an infectious microbiologic disease of the teeth that results in localized dissolution and destruction of the calcified tissue. Dental caries is a mulitifactorial disease, which is caused by host, agent, and environmental factors. The time factor is important for the development and progression of dental caries. A wide group of microorganisms are identified from carious lesions of which S. mutans , Lactobacillus acidophilus , and Actinomyces viscosus are the main pathogenic species involved in the initiation and development of dental caries. In India, surveys done on school children showed caries prevalence of approximately 58%. Surveys among the U.S. population showed an incidence of 45.3% in children and 93.8% in adults with either past or present coronal caries. Huge amounts of money and time are spent in treating dental caries. Hence, the prevention and control of dental caries is the main aim of public health, eventually the ultimate objective of public health is the elimination of the disease itself. Recently, dental caries vaccines have been developed for the prevention of dental caries. These dental caries vaccines are still in the early stages.en_US
dc.description.affiliationDepartment of Preventive and Community Dentistry, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences, Deemed University, Sawangi, Wardha Maharashtra, 442 004, India. kmshivakumar@rediffmail.comen_US
dc.identifier.citationShivakumar KM, Vidya SK, Chandu GN. Dental caries vaccine. Indian Journal of Dental Research. 2009 Jan-Mar; 20(1): 99-106en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/51685
dc.language.isoengen_US
dc.source.urihttps://www.ijdr.inen_US
dc.subject.meshAnimals
dc.subject.meshBacterial Vaccines --administration & dosage
dc.subject.meshCross Reactions
dc.subject.meshDental Caries --immunology
dc.subject.meshDental Caries --microbiology
dc.subject.meshDental Caries --prevention & control
dc.subject.meshDrug Delivery Systems
dc.subject.meshHealth Policy --economics
dc.subject.meshHumans
dc.subject.meshStreptococcus mutans --immunology
dc.subject.meshVaccination --methods
dc.titleDental caries vaccine.en_US
dc.typeJournal Articleen_US
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