Micronodular thymoma with lymphoid stroma: As benign as it sounds

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dc.contributor.authorChaudhary, Ken_US
dc.contributor.authorGala, Ren_US
dc.contributor.authorMehta, Jen_US
dc.date.accessioned2025-06-19T05:55:12Z
dc.date.available2025-06-19T05:55:12Z
dc.date.issued2025-03
dc.description.abstractMicronodular thymoma (MNT) is a rare subtype of thymoma (reported incidence is approximately 1–5%). We report a case received as a core biopsy from the “right lung mass” of a 31?year?old female. CT scan showed an 8.1 cm large well?defined mass lesion in the right middle lobe, causing indentation and mild compression of the right atrium. Microscopically, the biopsy showed a thymic neoplasm comprised of multiple discrete and coalescing nodules of bland epithelioid tumor cells separated by an epithelial cell?free lymphocyte?rich stroma. On immunohistochemistry, cytokeratin highlighted the thymic epithelial cells. The lymphoid cells showed a naive T?cell phenotype (TdT+ CD 3+). It is worthwhile recognizing this rare variant of thymoma as almost all the patients present with localized low stage disease with rare/no reports of recurrences or distant metastases.en_US
dc.identifier.affiliationsDepartment of Histopathology, Neuberg Oncopath Reference Laboratory, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Histopathology, Neuberg Oncopath Reference Laboratory, Mumbai, Maharashtra, Indiaen_US
dc.identifier.affiliationsDepartment of Histopathology, Neuberg Oncopath Reference Laboratory, Mumbai, Maharashtra, Indiaen_US
dc.identifier.citationChaudhary K, Gala R, Mehta J. Micronodular thymoma with lymphoid stroma: As benign as it sounds. Indian Journal of Pathology & Microbiology. 2025 Mar; 68(1): 216-218en_US
dc.identifier.issn0377-4929
dc.identifier.issn0974-5130
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/249958
dc.languageenen_US
dc.publisherWolters Kluwer - Medknowen_US
dc.relation.issuenumber1en_US
dc.relation.volume68en_US
dc.source.urihttps://doi.org/10.4103/ijpm.ijpm_585_23en_US
dc.subjectLung massen_US
dc.subjectmicronodularen_US
dc.subjectthymomaen_US
dc.titleMicronodular thymoma with lymphoid stroma: As benign as it soundsen_US
dc.typeJournal Articleen_US
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