Analysis of antimicrobial susceptibility pattern of ocular infections at Regional Ophthalmic Institute in India

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dc.contributor.authorNuzhat, Qudsiaen_US
dc.contributor.authorBandyopadhyay, Arkapalen_US
dc.contributor.authorChaurasia, Rakesh Chandraen_US
dc.contributor.authorSingh, Satya P.en_US
dc.contributor.authorSingh, Monicaen_US
dc.date.accessioned2020-04-23T08:01:41Z
dc.date.available2020-04-23T08:01:41Z
dc.date.issued2020-04
dc.description.abstractBackground: Ocular infections are a result of alteration in the normal microbial flora of eye. They are not only responsible for increase in morbidity varying from self-limiting trivial infection to sight threatening infection but also blindness.Methods: Patients with ocular infections were recruited at Regional Institute of Ophthalmology, Moti Lal Nehru Medical College, Allahabad, Uttar Pradesh. Bacterial profile in ocular infections and susceptibility pattern to commonly used antibiotics were analyzed amongst these patients. The isolated organism was then identified by colony morphology, gram stain and biochemical test following which in vitro susceptibility test was performed by Kirby-Bauer disc diffusion method and interpreted clinically.Results: Staphylococcus aureus and coagulase negative Streptococcus were most common etiological agents of ocular infections in the present study. It was observed that bacterial isolates were highly (in 100% of cases) susceptible to vancomycin and chloramphenicol among gram positive organisms. Gram negative organisms showed higher susceptibility to moxifloxacin, tobramycin and gentamycin. Pseudomonas was seen to have sensitivity towards ceftazidime and cefazolin.Conclusions: The present study gives an insight into use of ocular antimicrobials in northern India. These findings illustrate the need for constant bacterial surveillance before starting empirical treatment.en_US
dc.identifier.affiliationsDepartment of Pharmacology, Sri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, Indiaen_US
dc.identifier.affiliationsDepartment of Pharmacology, Government Medical College, Azamgarh, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, Moti Lal Nehru Medical College, Allahabad, Uttar Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of Microbiology, Moti Lal Nehru Medical College, Allahabad, Uttar Pradesh, Indiaen_US
dc.identifier.citationNuzhat Qudsia, Bandyopadhyay Arkapal, Chaurasia Rakesh Chandra, Singh Satya P., Singh Monica. Analysis of antimicrobial susceptibility pattern of ocular infections at Regional Ophthalmic Institute in India. International Journal of Basic & Clinical Pharmacology. 2020 Apr; 9(4): 642-646en_US
dc.identifier.issn2319-2003
dc.identifier.issn2279-0780
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/200586
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber4en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org/10.18203/2319-2003.ijbcp20201192en_US
dc.subjectAntibioticsen_US
dc.subjectBacteriaen_US
dc.subjectInfectionsen_US
dc.subjectOcularen_US
dc.subjectResistanceen_US
dc.titleAnalysis of antimicrobial susceptibility pattern of ocular infections at Regional Ophthalmic Institute in Indiaen_US
dc.typeJournal Articleen_US
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