EVALUATION OF SERUM C REACTIVE PROTEIN IN ACUTE APPENDICITIS AND ITS CORRELATION WITH HISTOPATHOLOGY

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dc.contributor.authorKarthik, Dr K.en_US
dc.contributor.authorKumar, M Shravanen_US
dc.date.accessioned2023-08-09T05:59:18Z
dc.date.available2023-08-09T05:59:18Z
dc.date.issued2022-12
dc.description.abstractBackground: Acute appendicitis is the most common abdominal surgical emergency, but its diagnosis remains an enigmatic challenge, plagued by a high rate of negative explorations. There is no single reliable test with satisfactory sensitivity and specificity. Ultrasonography is not often available at a rural surgical setup. This study is intended to evaluate the importance Aim: of serum C-reactive protein (CRP) level estimation in diagnosis of acute appendicitis, by comparing with histopathology report. In a Methods: prospective study,100 patients clinically diagnosed as acute appendicitis were selected by purposive sampling method and evaluated as per criteria for serum CRP levels, leucocyte count preoperatively and were followed up postoperatively with histopathology reports. The data was analysed for finding the significance of serum CRP in the diagnosis of acute appendicitis. CRP was positive in 75 of the 77 patients who Results: had histologically proven acute appendicitis and in 3 with normal appendix. The sensitivity, specificity and diagnostic accuracy were 97.4%, 86.96% and 95% respectively. Leucocytosis and neutrophilia when used alone were not specific for acute appendicitis, but when combined with CRP value, diagnostic accuracy was high. Ultrasonography was useful in establishing alternative diagnoses, but had low sensitivity for acute appendicitis. CRP contains important diagnostic information and hence should always Interpretation & Conclusion: be included in the diagnostic workup of acute appendicitis. Since acute appendicitis is very unlikely in those patients with normal WBC count and CRP value, conservative treatment is advised.This study does not undercut the skill of an experienced surgeon in diagnosing acute appendicitis, but CRP estimation compliments clinical diagnosis.en_US
dc.identifier.affiliationsMBBS MS FMAS DNB Surgical Oncology S/o Dr.k.subhash, Laxmi ENT Nursing Home H No: 5-6-202, Saraswathi Nagar, Nizamabad Telangana, Indiaen_US
dc.identifier.affiliationsMBBS DNB General Surgery H No: 11-1-223, Behind Sravya Gardens, Neelakanta Nagar, Nizamabad, Telangana, Indiaen_US
dc.identifier.citationKarthik Dr K., Kumar M Shravan. EVALUATION OF SERUM C REACTIVE PROTEIN IN ACUTE APPENDICITIS AND ITS CORRELATION WITH HISTOPATHOLOGY. Indian Journal Of Applied Research. 2022 Dec; 12(12): 45-48en_US
dc.identifier.issn2249-555X
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/221318
dc.languageenen_US
dc.publisherIndian Society For Health And Advanced Researchen_US
dc.relation.issuenumber12en_US
dc.relation.volume12en_US
dc.source.urihttps://www.doi.org/10.36106/ijar/7401746en_US
dc.subjectAppendicitisen_US
dc.subjectAppendectomyen_US
dc.subjectC reactive proteinen_US
dc.subjectinflammatory variablesen_US
dc.titleEVALUATION OF SERUM C REACTIVE PROTEIN IN ACUTE APPENDICITIS AND ITS CORRELATION WITH HISTOPATHOLOGYen_US
dc.typeJournal Articleen_US
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