Adverse Effects of Proton Pump Inhibitors use Among South Asian Population Systematic Review

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dc.contributor.authorAla, Samprithen_US
dc.contributor.authorSaruveish, Moganen_US
dc.contributor.authorElkin, Cook Danielen_US
dc.contributor.authorImran, Junaiden_US
dc.contributor.authorTarboush, Bilal Abuen_US
dc.contributor.authorMuthusamy, Vinoshinien_US
dc.date.accessioned2024-09-24T08:06:46Z
dc.date.available2024-09-24T08:06:46Z
dc.date.issued2023-04
dc.description.abstractBackground: This systematic review aims to identify the adverse effects of Proton Pump Inhibitors (PPI) among the South Asian population.Methods: A literature review was conducted using PubMed and EBSCO databases following the PRISMA guidelines. The search was performed between December 2022 and February 2023 using the Population, Intervention, Control, and Outcome (PICO) framework to develop a search syntax. Inclusion and exclusion criteria were established, and the search terms were used to identify relevant articles.Results: The search identified studies conducted in India, Pakistan, Bangladesh, and Indonesia. The adverse effects of PPI use in this population included acute kidney injury, an increased risk of osteoporosis and fracture, tubulointerstitial nephritis, QT prolongation and an increased risk of torsade's de pointes, diabetic nephropathy, an increased risk of thrombosis when combined with clopidogrel, constipation, and vitamin B12 deficiency.Conclusion: The use of PPIs among the South Asian population is associated with several adverse effects, including an increased risk of serious health conditions. Clinicians should exercise caution when prescribing PPIs to this population and weigh the benefits against the potential risks. Further research is needed to better understand the adverse effects of PPI use among South Asians.en_US
dc.identifier.affiliationsAvalon University School of Medicine,Curacao, Icelanden_US
dc.identifier.affiliationsFaculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Malaysiaen_US
dc.identifier.affiliationsAvalon University School of Medicine,Curacao, Icelanden_US
dc.identifier.affiliationsMedical College Peshawar, Pakistanen_US
dc.identifier.affiliationsFaculty of Medicine, Universite Djillali Liabes-Sidi Bel Abbes, Algeriaen_US
dc.identifier.affiliationsKementerian Kesihatan, Malaysiaen_US
dc.identifier.citationAla Samprith, Saruveish Mogan, Elkin Cook Daniel, Imran Junaid, Tarboush Bilal Abu, Muthusamy Vinoshini. Adverse Effects of Proton Pump Inhibitors use Among South Asian Population Systematic Review. International Journal of Medical Research & Health Sciences. 2023 Apr; 12(4): 1-8en_US
dc.identifier.issn2319-5886
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/230965
dc.languageenen_US
dc.publisherSumathi Publicationsen_US
dc.relation.issuenumber4en_US
dc.relation.volume12en_US
dc.source.urihttps://www.ijmrhs.com/medical-research/adverse-effects-of-proton-pump-inhibitors-use-among-south-asian-population-systematic-review-97536.htmlen_US
dc.subjectSouth Asianen_US
dc.subjectProton Pump Inhibitorsen_US
dc.subjectAdverse effectsen_US
dc.subjectPpi useen_US
dc.subjectSide effectsen_US
dc.titleAdverse Effects of Proton Pump Inhibitors use Among South Asian Population Systematic Reviewen_US
dc.typeJournal Articleen_US
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