Glycosylation index in type 2 diabetic patients with nephropathy

dc.contributor.authorPimpa Ratchawanen_US
dc.contributor.authorJindarat Trakulthongen_US
dc.contributor.authorWisut Kangwantrakulen_US
dc.contributor.authorLimthong Promdeeen_US
dc.date.accessioned2011-02-24T04:34:33Z
dc.date.available2011-02-24T04:34:33Z
dc.date.created2011-01-08en_US
dc.date.issued2011-01-08en_US
dc.description.abstractBackground and objective : Glycosylation index is composed of glycosylation gap (GG), hemoglobin glycation index (HGI), fructosamine glycation index (FGI).\  The indeces are index calculated based on blood glucose (BG), fructosamine (F), and glycated hemoglobin (HbA1C).\  The purpose of this study was to compare these indices in type 2 diabetic patients (T2DM) with various\  stages of nephropathy.Methods:\  HbA1C, BG and F were obtained from 104 T2DM patients (37 males, 67 females) at a single clinical visit at Buddhachinnaratana Hospital, Pitsanulok.\  The stages of nephropathy was divided into 3 groups according to albuminuria level; no nephropathy (n = 57), microalbuminuria (n = 29), and advanced nephropathy (n = 18).Results : Mean\±SD HbA1C = 7.9\±1.7%, F = 279\±69 mol/L, BG = 7.0\±1.9 mmol/L, GG = 0.0\±2.37, HGI = -0.23\±1.47, and FGI = -0.21\±63 were found in all subjects.\  Mean GG (0.55\±0.8), HGI (0.70\±1.5), and HbA1C (9.0\±1.8%) in patients with advanced nephropathy was significantly different from those with no nephropathy and microalbuminuria (P \< 0.05),Conclusions :\  Increasing levels of HbA1C indicate with worsening nephropathy in T2DM.\ Key words: Glycosylation index; type 2 diabetes mellitus; Microalbuminuria; Nephropathy\ en_US
dc.identifier.citationSrinagarind Medical Journal (SMJ); Vo. 25 No. 4 October-December 2010; 280-286en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/134089
dc.language.isoen_USen_US
dc.publisherFaculty of Medicine, Khon Kaen Universityen_US
dc.rightsAcademic Affairs, Faculty of Medicine, Khon Kaen University, KhonKaen, Thailanden_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/SMJ/issue/archiveen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/SMJ/article/view/4610en_US
dc.titleGlycosylation index in type 2 diabetic patients with nephropathyen_US
dc.typeOriginal Articlesen_US
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