Comparative analysis of high dose methyldopa and low dose methyldopa with nifedipine in terms of blood pressure in cases of pregnancy induced hypertension

dc.contributor.authorQuratulainen_US
dc.contributor.authorUlAbidin, Zainen_US
dc.contributor.authorAslam, Sidraen_US
dc.date.accessioned2023-11-27T10:14:49Z
dc.date.available2023-11-27T10:14:49Z
dc.date.issued2021-04
dc.description.abstractObjective: Comparison between Methyldopa and combination of Methyldopa and Nifedipine in terms of mean change in blood pressure in pregnancy induced hypertension. Material and methods: This randomized controlled was conducted at Depart Obstetrics and Gynecology DHQ Okara. Total 80 women with pregnancy induced hypertension having age range from 20-40 years and with gestational age 20-40 weeks were selected. Results: Mean age of the patients was 30.81 ± 5.670 years, mean age of patients of group A was 31.50 ± 5.809 years and mean age of group B was 30.13 ± 5.515 years. Mean gestational age was 30.17 ± 5.981 weeks, mean gestational age of patients of group A was 29.70 ± 6.329 weeks and mean gestational age of patients of group B was 6.329 ± 5.650 weeks. In group A, mean diastolic blood pressure was decrease from 101.2250 ± 4.97938 to 84.5000 ± 3.26599 and in group B from 107.7750 ± 7.18434 to 82.5000 ± 2.25320. Comparison of mean decrease in diastolic blood pressure between group A (High dose Methyldopa) and group B (Low dose Low dose Methyldopa with Nifedipine) was done. Mean decrease in diastolic blood pressure in group A was 16.72 ± 3.935 and in group B was 25.28 ± 6.876. Statistically significant difference of mean decrease in diastolic blood pressure between the both groups was noted with p value 0.000. Conclusion: Results of this study showed that Low dose Methyldopa with Nifedipine combination is more effective as compared to High dose Methyldopa to reduce diastolic blood pressure in pregnant women suffering from pregnancy induced hypertension.en_US
dc.identifier.affiliationsWoman Medical Officer, DHQ, Okara, Pakistanen_US
dc.identifier.affiliationsMedical Officer, Department of Orthopedic Surgery, DHQ Hospital Vehari, Pakistanen_US
dc.identifier.affiliationsEx-House Officer, CMH Lahore, Pakistanen_US
dc.identifier.citationQuratulain, UlAbidin Zain, Aslam Sidra. Comparative analysis of high dose methyldopa and low dose methyldopa with nifedipine in terms of blood pressure in cases of pregnancy induced hypertension. IJHS Medical Association . 2021 Apr; 8(2): 9-13en_US
dc.identifier.issn2349-7033
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/226549
dc.languageenen_US
dc.publisherIJHS Medical Associationen_US
dc.relation.issuenumber2en_US
dc.relation.volume8en_US
dc.source.urihttps://www.ijhsonline.com/index.php/IJHS/article/view/149/77en_US
dc.subjectDiastolic blood pressureen_US
dc.subjectMethyldopaen_US
dc.subjectNifedipineen_US
dc.subjectPregnancy induced hypertensionen_US
dc.subjectSystolic blood pressureen_US
dc.titleComparative analysis of high dose methyldopa and low dose methyldopa with nifedipine in terms of blood pressure in cases of pregnancy induced hypertensionen_US
dc.typeJournal Articleen_US
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