Exploring the Correlation Between Fibrinogen-to-Albumin Ratio and Contrast-Induced Nephropathy in the Study Population

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dc.contributor.authorMridha, Sohelen_US
dc.contributor.authorRashid, Md. Mamunuren_US
dc.contributor.authorKundu, Samiren_US
dc.contributor.authorMomen, Abdulen_US
dc.contributor.authorAfroza, Nahiden_US
dc.contributor.authorMasum, Mahmudul Hasanen_US
dc.contributor.authorAlam, Iftekharen_US
dc.date.accessioned2024-12-07T11:12:01Z
dc.date.available2024-12-07T11:12:01Z
dc.date.issued2024-01
dc.description.abstractBackground: Contrast-Induced Nephropathy (CIN) presents a significant risk in non-ST elevation acute coronary syndrome (NSTE-ACS) patients undergoing percutaneous coronary intervention (PCI). This study investigates the association between the Fibrinogen-to-Albumin Ratio (FAR) and CIN in such patients. Material & Methods: This cross-sectional study was conducted at the Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, from June 2019 to May 2020. 200 NSTE-ACS patients undergoing PCI were categorized into two groups based on FAR: Group I (FAR ? 0.106, n=100) and Group II (FAR < 0.106, n=100). Clinical parameters, including pulse rate, blood pressure, and biochemical markers, were analyzed. The incidence of CIN and the role of FAR as a predictive marker were statistically evaluated. Results: Baseline clinical parameters showed no significant differences between the groups, with pulse rates averaging 88.8�.4 bpm in Group I and 87.7�.4 bpm in Group II (p=0.62). Troponin I levels were higher in Group I (42.1�.6 ng/dl) compared to Group II (35.5�.6 ng/dl, p=0.07). Group I also exhibited higher hemoglobin levels (12.5�5 gm/dl vs. 12.0�5 gm/dl in Group II, p=0.02). The incidence of CIN was significantly higher in Group I at 12%, compared to 2% in Group II. FAR was identified as a significant predictor of CIN, with an odds ratio of 11.45 (p=0.006). Conclusions: The study establishes FAR as a significant independent predictor of CIN in NSTE-ACS patients undergoing PCI. These findings suggest that FAR can be an effective biomarker for assessing CIN risk, potentially guiding more tailored patient management strategies in this high-risk group.en_US
dc.identifier.affiliationsAssistant Registrar, Department of Cardiology, National Institute of Cardiovascular Disease, Dhaka, Bangladesh. Email: sohel11295@gmail.com, Orcid ID: 0009-0002-5523-7286en_US
dc.identifier.affiliationsProfessor, Department of Cardiology, National Institute of Cardiovascular Disease, Dhaka, Bangladesh. Email: dr.mamunur@hotmail.com, Orcid Id: 0009-0006-8542644Xen_US
dc.identifier.affiliationsAssociate Professor, Department of Cardiology, National Institute of Cardiovascular Disease, Dhaka, Bangladesh. Email: samirkundu06@gmail.com, Orcid ID: 0009-0004-7218-9276en_US
dc.identifier.affiliationsAssociate Professor, Department of Cardiology, National Institute of Cardiovascular Disease, Dhaka, Bangladesh. Email:abdulmomen71@gmail.com, Orcid ID:0009-0005-1861-833Xen_US
dc.identifier.affiliationsMedical Officer, Department of Hematology, Dhaka Medical College, Dhaka, Bangladesh. Email: dr.nahidafroza@yahoo.com, Orcid ID: 0009-0002-4955-6715en_US
dc.identifier.affiliationsRegistrar, Department of Cardiology, National Institute of Cardiovascular Disease, Dhaka, Bangladesh. Email: mhmasum41@gmail.com, Orcid ID: 0009-0003-0822-3946en_US
dc.identifier.affiliationsAssistant Professor, Department of Cardiology, National Institute of Cardiovascular Disease, Dhaka, Bangladesh. Email: iftekhar1029@gmail.com, Orcid ID: 0000-0002-0469-0550en_US
dc.identifier.citationMridha Sohel, Rashid Md. Mamunur, Kundu Samir, Momen Abdul, Afroza Nahid, Masum Mahmudul Hasan, Alam Iftekhar. Exploring the Correlation Between Fibrinogen-to-Albumin Ratio and Contrast-Induced Nephropathy in the Study Population. Annals of International Medical and Dental Research. 2024 Jan; 10(1): 50-61en_US
dc.identifier.issn2395-2822
dc.identifier.issn2395-2814
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/241047
dc.languageenen_US
dc.publisherSociety for Health Care & Research Developmenten_US
dc.relation.issuenumber1en_US
dc.relation.volume10en_US
dc.source.urihttps://doi.org/10.53339/aimdr.2024.10.1.7en_US
dc.subjectFibrinogen-to-Albumin Ratio (FAR)en_US
dc.subjectContrast-Induced Nephropathy (CIN)en_US
dc.subjectBiomarkersen_US
dc.subjectCardiovascularen_US
dc.titleExploring the Correlation Between Fibrinogen-to-Albumin Ratio and Contrast-Induced Nephropathy in the Study Populationen_US
dc.typeJournal Articleen_US
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