Enhancement of virulence of Entamoeba histolytica by histamine in vitro.

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dc.contributor.authorKhan, M Aen_US
dc.contributor.authorSen, P Cen_US
dc.contributor.authorMishra, Ben_US
dc.date.accessioned2009-05-28T14:17:06Z
dc.date.available2009-05-28T14:17:06Z
dc.date.issued1990-04-01en_US
dc.description.abstractThree isolates of E. histolytica isolated and maintained in modified Boeck and Drbohlav's medium and the axenic nonpathogenic strain NIH-200 maintained in Diamond's TPS-1 medium were used to assess the effect of histamine added to the cultures on their pathogenicity in just weaned rats of Charles Foster strain. Initially when the three polyxenic isolates were examined for their Pathogenicity after growing them with graded concentrations of histamine viz. M-2 through M-6 (log dilutions of the molar concentration of histamine dihydrochloride) the caecal scores were significantly enhanced in cultures grown with M-2 and M-3 concentrations. Subsequently NIH-200 strain was examined similarly after growing it with 20 micrograms/ml of histamine dihydrochloride through three generations. The Neal's caecal score of NIH-200 increased significantly stepwise up to second subculture and became stabilised at third generation with histamine.en_US
dc.description.affiliationDepartment of Microbiology, Banaras Hindu University, Varanasi, India.en_US
dc.identifier.citationKhan MA, Sen PC, Mishra B. Enhancement of virulence of Entamoeba histolytica by histamine in vitro. Indian Journal of Experimental Biology. 1990 Apr; 28(4): 376-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/60510
dc.language.isoengen_US
dc.source.urihttps://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijeb/ijeb0.aspen_US
dc.subject.meshAmebiasis --parasitologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshEntamoeba histolytica --pathogenicityen_US
dc.subject.meshEntamoebiasis --parasitologyen_US
dc.subject.meshHistamine --pharmacologyen_US
dc.subject.meshRatsen_US
dc.subject.meshVirulenceen_US
dc.titleEnhancement of virulence of Entamoeba histolytica by histamine in vitro.en_US
dc.typeJournal Articleen_US
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