Detection of foot-and-mouth disease virus type O in recovered as well as healthy cattle to study carrier status in Assam

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dc.contributor.authorDAS, LEENAen_US
dc.contributor.authorSHARMA, KRISHNAen_US
dc.contributor.authorBORAH, PROBODHen_US
dc.contributor.authorBARMAN, NAGENDRA NATHen_US
dc.contributor.authorKALITA, DHRUBA JYOTIen_US
dc.contributor.authorHUSSAIN, IFTIKARen_US
dc.contributor.authorDEVI, BHANITAen_US
dc.date.accessioned2023-08-09T06:20:16Z
dc.date.available2023-08-09T06:20:16Z
dc.date.issued2022-03
dc.description.abstractFoot and mouth disease (FMD), one of the most contagious diseases of animals, affects different host species including wild animals. Asymptomatic FMD recovered animals may remain as carrier, which may be threat to other healthy animals. Hence, it is necessary to monitor the carrier status of the FMD recovered animals to effectively prevent further spread of the disease. Out of all the seven serotypes of FMD, O serotype is most commonly found in livestock. Therefore, in the present study, we chose to detect serotype ‘O’ in oropharyngeal fluid (OP) and to quantify cytokines, viz. IL-1?, IL-1? and IL-2. A total of 30 OP fluids and 30 blood samples were collected from 10 animals (1 in-contact healthy animal) for 3 months post infection. FMD O serotype could be detected in all the animals (100%). The RQ values were found to be 0.014 to 63.118 and 0.162 to 46.889 for IL-1? and IL-1? genes respectively, while insignificant RQ values were obtained for IL-2. In the second and third months, two animals showed down regulation for IL-1? gene, while IL-1? and IL-2 genes were down regulated in 7 animals and in all 10 animals, respectively for all the three months.en_US
dc.identifier.affiliationsDepartment of Animal Biotechnologyen_US
dc.identifier.affiliationsDepartment of Veterinary Microbiologyen_US
dc.identifier.affiliationsDepartment of Veterinary Biochemistry, College of Veterinary Science, Khanapara, Guwahati - 781 022, Assam, Indiaen_US
dc.identifier.affiliationsDistrict Animal Husbandry Office, Ara, Bhojpur, Bihar, Indiaen_US
dc.identifier.citationDAS LEENA, SHARMA KRISHNA, BORAH PROBODH, BARMAN NAGENDRA NATH, KALITA DHRUBA JYOTI, HUSSAIN IFTIKAR, DEVI BHANITA. Detection of foot-and-mouth disease virus type O in recovered as well as healthy cattle to study carrier status in Assam. Indian Journal of Experimental Biology. 2022 Mar; 60(3): 200-206en_US
dc.identifier.issn0975-1009
dc.identifier.issn0019-5189
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/222472
dc.languageenen_US
dc.publisherCSIR-NIScPRen_US
dc.relation.issuenumber3en_US
dc.relation.volume60en_US
dc.source.urihttps://doi.org/10.56042/ijeb.v60i03.34804en_US
dc.subjectCytokinesen_US
dc.subjectInterleukinsen_US
dc.subjectLivestocken_US
dc.subjectOropharyngeal fluiden_US
dc.titleDetection of foot-and-mouth disease virus type O in recovered as well as healthy cattle to study carrier status in Assamen_US
dc.typeJournal Articleen_US
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