Sericin A Boon to Medical and Dentaldoctors – A Review
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Date
2023-09
Journal Title
Journal ISSN
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Publisher
Sumathi Publications
Abstract
Silk sericin is a natural polymer produced by the silkworm, Bombyx mori, which surroundsand keeps together two fibroin filaments in silk thread used in the cocoon. The recovery andreuse of sericin usually discarded by the textile industry not only minimizes environmentalissues but also has a high scientific and commercial value. The physicochemical properties ofthe molecule are responsible for numerous applications in biomedicine and are influenced bytheextractionmethodandsilkwormlineage,whichcanleadtovariationsinmolecularweightand amino acid concentration of sericin. The presence of highly hydrophobic amino acids andtheir antioxidant potential make it possible for sericin to be applied in the food and cosmeticindustry.Themoisturizingpowerallowsindicationsasatherapeuticagentforwoundhealing,stimulatingcellproliferation,protectionagainstultravioletradiation,andformulatingcreamsandshampoos.Theantioxidantactivityassociatedwiththelowdigestibilityofsericinexpandsthe application in the medical field, such as antitumour, antimicrobial and anti-inflammatoryagent,andanticoagulant,actsincolonhealth,improvingconstipationandprotectingthebodyfromobesitythroughimprovedplasmalipidprofile.Inaddition,thepropertiesofsericinallowits application as a culture medium and cryopreservation, in tissue engineering and for drugdelivery, demonstrating its effective use, as an important biomaterial. The present review onsericin describes its properties and application in various fields
Description
Keywords
Silk, sericin, biomedical, dental, biomaterial, biodegradable, biocompatible
Citation
Devi Devarathnamma MV, Bhat Geeta, Kudva Praveen. Sericin A Boon to Medical and Dentaldoctors – A Review. International Journal of Clinical and Biomedical Research. 2023 July; 9(3): 1-10