Effect of General Anesthesia With Epidural Versus General Anesthesia Alone on Requirement of Inhalational Agents and Peri Operative Analgesic in Patient Undergoing Major Abdominal Surgery
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Date
2024-01
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FORUM: Fraternity of national Research & pUblication Society of Medical sciences
Abstract
Background: Abdominal onco surgeries are of longer duration and patients may experience severe pain peri operatively. We have hypothesized that patient will require more IV analgesic drugs like opioids, if only general anaesthesia is given, but need for IV analgesic will be reduced if Epidural anaesthesia is combined with General anaesthesia. Here we have compared 32 patients (sixteen from each group) undergoing major abdominal onco surgery under general anaesthesia alone versus epidural along with general anaesthesia with use of Ropivacaine and Fentanyl for epidural infusion, and observed that patient with general and epidural anaesthesia required smaller dose of IV opioids and minimal use of inhalational agent intra operatively. Methods: • Objectives are: Need of inhalational agent, to asses perioperative pain relief and need of iv analgesic drugs in patient undergoing major abdominal onco surgeries under epidural with general anesthesia as compared to general anesthesia only. • After Institutional Ethics committee approval (IEC/BU/133/FACULTY/2/251), CTRI registration (CTRI/2022/02/039912) and patient’s consent, 32 patients were randomly allocated in Group GA (n=16) and Group EG (n=16), undergoing major abdominal onco surgeries. Group GA receiving general anaesthesia only, Group EG receiving epidural with general anaesthesia. Parameters mentioned in aims and objectives were compared. Results: Study revealed statistically significant difference between two groups, with mean value for use of Sevoflurane was 26.88 in EA with GA group and 44.94 in GA only group with P value <0.001. Conclusions: EA with GA group required less inhalational anaesthetic agent and iv analgesic agents as compared to GA group only.
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Keywords
Abdominal onco surgeries, Epidural anaesthesia with Ropivacaine, Inhalational agent.
Citation
Patel Alpa, Parikh Ushma, Desai Ruchiben Maheshbhai. Effect of General Anesthesia With Epidural Versus General Anesthesia Alone on Requirement of Inhalational Agents and Peri Operative Analgesic in Patient Undergoing Major Abdominal Surgery. Indian Journal of Applied Basic Medical Sciences. 2024 Jan; 26A(1): 1-10